Immunofluorescence detection of the CLAG3 proteins, which play a role in resistance to some antimalarial compounds. Credit: Mira et al, 2019 Resistance to antimalarial drugs is thought to result mainly from changes in the parasite’s genome. However, P. falciparum can also develop resistance to some antimalarial compounds by epigenetic changes, according to a new study […]Continue Reading ...
A comprehensive analysis of sewage collected in 74 cities in 60 countries has yielded the first, comparable global data, which show the levels and types of antimicrobial resistant bacteria that are present in mainly healthy people in these countries. The National Food Institute, Technical University of Denmark, headed the study, which was conducted by an […]Continue Reading ...
Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used. Recurrence of target tumors may therefore take place, which is a serious problem. It has been well recognized that genetic mutation is somehow induced in the cancer cells on […]Continue Reading ...
Feb 19 2019 By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to the study published in the journal ‘Microbiome’, those mechanisms are more […]Continue Reading ...
Feb 13 2019 The new Deeplex®-MycTB mycobacterial antibiotic resistance test, developed by GenoScreen, has been used by an international research team in a molecular epidemiology study published in The Lancet Infectious Diseases. This study highlights the spread of tuberculosis strains resistant to first-line antibiotics, not detected by actual international tests. 1: Visualisation and interpretation of […]Continue Reading ...
The UK government has launched a 5-year action plan outlining how the nation intends to contribute to the containment and control of antimicrobial resistance by the year 2040. Kateryna Kon | Shutterstock The government’s goals include a 10% reduction in the number of drug-resistant infections by 2025 and the prevention of at least 15,000 new […]Continue Reading ...
The Staphylococcus aureus bacterium is one of the commonest pathogens and can even cause sepsis. The new antibiotic dalbavancin is very effective against many bacterial pathogens. However, resistance to the antibiotic was seen to develop during the long-term treatment of a patient with an infection caused by an implanted cardiac device. A team of researchers […]Continue Reading ...
Crystal structure of a portion of the HER2 protein. Credit: RCSB PDB Metastatic breast cancers treated with hormone therapy can become treatment-resistant when they acquire mutations in the human epidermal growth factor receptor 2 (HER2) that were not present in the original tumor, reports a team led by scientists from Dana-Farber Cancer Institute and the […]Continue Reading ...
Data released today by the European Centre for Disease Prevention and Control (ECDC) and European Food Safety Authority (EFSA) reveal that antimicrobials used to treat diseases that can be transmitted between animals and humans, such as campylobacteriosis and salmonellosis, are becoming less effective. Vytenis Andriukaitis, EU Commissioner for Health and Food Safety, said: “The report […]Continue Reading ...
Scientists from DTU have discovered that a combination of two common antibiotics can eliminate multi-drug resistant E. coli causing urinary tract infections; this combination treatment could become an effective measure against antibiotic resistance A group of scientists in Denmark is trying to get one step ahead in the battle against antibiotic resistance. Today, many disease-causing […]Continue Reading ...
The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract. However, it can also cause life-threatening infections, especially in immunocompromised patients. These infections are usually treated with the drug fluconazole, which inhibits the synthesis of ergosterol in Candida. Ergosterol fulfils similar important functions in fungi as cholesterol in […]Continue Reading ...
When President Donald Trump demands a border wall or threatens to deport young unauthorized immigrants, one of the loudest opposition voices comes from the son of Mexican immigrants — who also happens to be California’s top lawyer. Democrat Xavier Becerra, the state’s first Latino attorney general, is not only one of Trump’s biggest critics, he […]Continue Reading ...
Study identifies key step in spread of drug resistance, opportunity for intervention Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems. Acinetobacter baumannii causes life-threatening lung and bloodstream infections in hospitalized people. Such infections are among the most difficult […]Continue Reading ...
Increased levels of antibiotic resistant bacteria in the environment may have different causes. It could be a consequence of on-site selection from antibiotic residues in the environment, hence promoting the evolution of new forms of resistance. Alternatively, it is simply due contamination by fecal bacteria that often tend to be more resistant than other bacteria. […]Continue Reading ...
Researchers at Osaka University have discovered that polymyxin E-resistant Escherichia coli is widely prevalent among people living in rural Vietnam. Kateryna Kon | Shutterstock Polymyxin E is an antibiotic that is used to prevent the growth of Gram-negative bacteria such as E.coli and Pseudomonas aeruginosa. It is one of only a few remaining drugs that […]Continue Reading ...
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