Immune checkpoint inhibitors, such as the anti-PD-1 antibody pembrolizumab, have become important tools for managing non-small-cell lung cancer (NSCLC). Assessing the level of programmed death ligand 1 (PD-L1) expressed by a tumor can help clinicians determine how the patient should be treated. A report in The Journal of Molecular Diagnostics describes a novel and rapid […]Continue Reading ...
A study provides new insight into how the stiffening of breast tissue plays a role in breast cancer development. By examining how mammary cells respond in a stiffness-changing hydrogel, bioengineers at the University of California San Diego discovered that several pathways work together to promote the transformation of breast cells into cancer cells. The work […]Continue Reading ...
Measurement of AHNAK2 helps physicians make challenging diagnostic decisions, according to a new study in The American Journal of Pathology Label-free digital pathology using infrared (IR) imaging with subsequent proteomic analysis for bladder cancer (BC) has revealed the first protein biomarker (AHNAK2) for BC. AHNAK2 differentiates between chronic cystitis (inflammation of the bladder) and a […]Continue Reading ...
Although currently laser surgery is a very popular tool for various vision disorders correction, it is still difficult to ensure proper control over the accuracy, efficiency and safety of such procedures. Therefore, Russian scientists proposed a new method that helps to describe tissue changes after such operations. This method was described in a series of […]Continue Reading ...
Lawmakers clashed over science, ethics and politics at a House hearing Thursday on using fetal tissue in critically important medical research, as the Trump administration reviews the government’s ongoing support for such studies. Research fields in which fetal tissue is used include HIV, childhood cancers, treatments that enlist the body’s immune system to battle cancer, […]Continue Reading ...
Micropores in fabricated tissues such as bone and cartilage allow nutrient and oxygen diffusion into the core, and this novel approach may eventually allow lab-grown tissue to contain blood vessels, according to a team of Penn State researchers. “One of the problems with fabrication of tissues is that we can’t make them large in size,” […]Continue Reading ...
Credit: Mary Ann Liebert, Inc., publishers A team of researchers developed a novel model of partial bladder outlet obstruction (pBOO) in female swine and used this model to show that even after inducing severe urinary outlet resistance and damage to the bladder, they could achieve significant improvements in bladder capacity through bladder reconstruction using acellular […]Continue Reading ...
The rotator cuff is a group of four muscles and tendons that stabilizes the shoulder joint. It also helps in the motion of the shoulder. Rotator cuff tear is the most common condition involving ailing shoulders. It happens due to normal muscle tissue wear and tear by repeating the same motion again and again, without […]Continue Reading ...
The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that could help clinicians predict which patients will respond best to particular treatments. The research, led by Queen Mary University of London, The Institute of Cancer Research, London, […]Continue Reading ...
Rutin, a bioflavonoid (plant pigment) found in certain vegetables and fruits, protects mice against snake venom by minimizing bleeding and inflammation, according to a study performed at the Butantan Institute, a research institution belonging to the government of São Paulo State in Brazil. The research focused on methods to combat the effects of envenomation by […]Continue Reading ...
A certain proportion of the adult population has not only white adipose (or fatty) tissue, but also the brown kind. This brown adipose tissue helps to convert sugar and fat into heat. People with brown adipose tissue are better at regulating their body temperature in the winter, and are less likely to suffer from excess […]Continue Reading ...
A team of University of Illinois at Urbana-Champaign researchers led by Professor Stephen Boppart has successfully visualized the tumor microenvironment of human breast tissue shortly after it was surgically removed from a patient in the operating room. The researchers achieved this using a new portable optical imaging system developed in Boppart’s lab. This work, which […]Continue Reading ...
Collagen is the fundamental building block of muscles, tissues, tendons, and ligaments in mammals. It is also widely used in reconstructive and cosmetic surgery. Although scientists have a good understanding about how it behaves at the tissue-level, some key mechanical properties of collagen at the nanoscale still remain elusive. A recent experimental study conducted by […]Continue Reading ...
In certain forms of cancer, connective tissue forms around and within the tumor. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumor in different ways. Now, a research team at Lund University in Sweden has identified three different types […]Continue Reading ...
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