Myelofibrosis is a severe and very rare hematological disease for which treatment has only been partially effective to date. Its low incidence rate is one of the reasons why effective therapies are still lacking. The H12O-CNIO Hematological Malignancies Clinical Research Unit at the Spanish National Cancer Research Centre (CNIO), which also encompasses professionals from the […]Continue Reading ...
FDA Approves Motegrity (prucalopride) for Adults with Chronic Idiopathic Constipation (CIC) Cambridge, Mass. – December 17, 2018 – Shire plc (LSE: SHP, NASDAQ: SHPG) has announced that the U.S. Food and Drug Administration (FDA) has approved Motegrity™ (prucalopride), a once-daily, oral treatment option for adults with Chronic Idiopathic Constipation (CIC).1 Motegrity, a selective serotonin-4 (5-HT4) […]Continue Reading ...
Albuminuria is a renal disease that is found to be independently associated with cardiovascular and renal problems without any links to diabetes. In latest ESC/ESH guidelines, microalbuminuria has been related to hypertension-mediated organ damages. While studying its effects and treatment, it was suggested to include albumin-to-creatinine ratio in the routine workup evaluation of the hypertensive […]Continue Reading ...
Relationship impairment (difficulty managing expectations and requirements within an intimate relationship) plays a role in explaining the association between symptom severity and those seeking treatment among post-9/11 military veterans. However, the role it plays is different for men and women. In men, relationship impairment appears to interfere with seeking treatment for post-traumatic stress disorder (PTSD) […]Continue Reading ...
A discovery by researchers from the School of Basic & Medical Biosciences and NIHR Guy’s and St Thomas’ Biomedical Research Centre could lead to new treatments for severe acne. Scientists found 15 genome regions linked to developing the condition. The study, published in Nature Communications, looked at the DNA of 26,722 people, including 5,602 who […]Continue Reading ...
THURSDAY, Dec. 6, 2018 — Recommendations have been developed for pharmacologic and nonpharmacologic treatment of psoriatic arthritis (PsA); the evidence-based guideline was published online Nov. 30 in Arthritis & Rheumatology. Jasvinder A. Singh, M.D., M.P.H., from the University of Alabama at Birmingham, and colleagues summarized the evidence supporting the benefits and harms of available pharmacologic […]Continue Reading ...
Research published today shows that circulating tumor cell count may provide an effective indicator of appropriate treatment choice for metastatic breast cancer. The risk of death was 35% lower among patients whose treatment was escalated according to the level of circulating tumor cells. Suzi44 | Shutterstock It has been estimated that more than 154,000 women […]Continue Reading ...
The American College of Rheumatology (ACR) and National Psoriasis Foundation (NPF) have released a joint treatment guideline for psoriatic arthritis (PsA) that provides evidence-based pharmacologic and non-pharmacologic recommendations on caring for treatment-naïve patients with active PsA and patients who continue to have active PsA despite treatment. It also includes recommendations for vaccinations, psoriatic spondylitis, predominant […]Continue Reading ...
Its effectiveness was proved in clinical trials A team of scientists of Ural Federal University headed by Prof. Vladimir Kublanov created a hardware-information system for brain disorders prophylaxis and treatment unrivaled both in Russia and throughout the world. The system developers published the article describing the system in the journal Mobile Information Systems (UK). According […]Continue Reading ...
Traumatic experiences can become deeply entrenched in a person’s memory. How can fears following a traumatic event be reduced in the long term and prevented from becoming a permanent stress-related disorder? Researchers at the Mainz University Medical Center have recently shed new light on these questions. The key to their approach lies in firmly anchoring […]Continue Reading ...
HIV infecting a human cell. Credit: NIH A study published in The Lancet HIV shows that HIV-2 is more pathogenic than previously demonstrated. The new findings indicate that early treatment should be applied to all patients with HIV, not only to those with HIV-1. “The study is unique in that we have followed cohort of […]Continue Reading ...
Today, the U.S. Food and Drug Administration cleared a mobile medical application (app) to help increase retention (the amount of time a patient participates) in an outpatient treatment program for individuals with opioid use disorder (OUD). The reSET-O app is a prescription cognitive behavioral therapy intended to be used in addition to outpatient treatment under […]Continue Reading ...
Providing supervised access to medical-grade heroin to people whose use continues after trying multiple traditional treatments has been successful in other countries, and should be piloted and studied in the United States, according to a new RAND Corporation study. Evidence from other nations suggests that prescribing heroin to be injected under medical observation — with […]Continue Reading ...
Credit: CC0 Public Domain A persistent challenge in HIV/AIDS treatment and prevention is medication adherence – getting patients to take their medication as required to get the best results. Currently, a once-daily pill to prevent HIV infection is available. However, adherence to a once-daily regimen can be difficult for some people. Researchers from the UNC […]Continue Reading ...
After over a decade of preclinical research and development, a new gene therapy treatment for Sickle Cell Anemia (SCA) is reversing disease symptoms in two adults and showing early potential for transportability to resource-challenged parts of the world where SCA is most common. Preliminary data from a pilot Phase 1-2 clinical trial testing the gene-addition […]Continue Reading ...
- Researchers uncover genes that play a key role in the inactivation of X chromosomes
- The case for the federal minister of health to recall them
- Regular theatre and cinema visits keeps depression away in seniors finds study
- Personalization techniques give a new lease of life to anticancer vaccines
- Research opens door to development of drug or vaccine for late-onset Alzheimer’s
- Single workout can boost metabolism for days
- UI study leads to better understanding of signaling capacity between neurons
- Gut microbiome plays role in immune system regulation, study finds
- How MAPK translocation leads to drug resistance in melanoma
- Increasing prevalence of antibiotic resistance in the U.S. linked with occasional use
- Mind-body exercises may improve cognition in older adults
- Hepatitis C drug can eliminate chikungunya, yellow fever virus
- Separating male and female mice changes the way they smell, shows study
- FDA Approves Genentech’s Tecentriq in Combination With Avastin and Chemotherapy for the Initial Treatment of Metastatic Non-Squamous Non-Small Cell Lung Cancer
- Mediterranean Diet for Osteoarthritis | About OA
- Successful bladder repair using silk fibroid scaffolds
- Quidel receives CE mark to use Sofia 2 Lyme+ Fluorescent Immunoassay with Sofia 2 analyzer
- Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets
- Research suggests a promising therapeutic target to treat or prevent metabolic disorders
- Split liver transplants could save children on wait list finds study