Breaking News
October 19, 2018 - Conceptual framework proposed to examine role of exercise in multiple sclerosis
October 19, 2018 - Near infrared spectroscopy technique for accurate evaluation of chondral injuries
October 19, 2018 - Shorter physician encounters associated with antibiotic prescribing
October 19, 2018 - In the Spotlight: Enjoying research and exploring opportunities
October 19, 2018 - Physical activity lowers cardiovascular mortality risk in frail older adults
October 19, 2018 - New imaging tool helps visualize how sound-induced vibrations travel through the ear
October 19, 2018 - Key insights into the application, production of bioactive materials
October 19, 2018 - New urea sorbent could speed up the development of wearable artificial kidney
October 19, 2018 - Intensive care patients’ muscles less able to use fats for energy
October 19, 2018 - FDA Advisory Committee Recommends Approval of Dsuvia for the Treatment of Moderate-to-Severe Acute Pain
October 19, 2018 - 48,XXXY syndrome – Genetics Home Reference
October 19, 2018 - Physical exercise improves the elimination of toxic proteins from muscles
October 19, 2018 - How a new system improved wait times for Stanford kidney transplant patients
October 19, 2018 - Nutrition has bigger positive impact on bone mass and strength than exercise
October 19, 2018 - Study finds lack of progress in media representation of nurses over last 20 years
October 19, 2018 - Many people have trouble understanding differences between OCD and OCPD
October 19, 2018 - New family planning app found to be as effective as modern methods
October 19, 2018 - Gastric Banding, Metformin Similar for Improving Glycemia
October 19, 2018 - Physiologist publishes findings on the role of the protein titin in muscle contraction
October 19, 2018 - What digital health companies need to do to succeed
October 19, 2018 - N. Carolina Sees Alarming Spike in Heart Infections Among Opioid Users
October 19, 2018 - Video monitoring of TB therapy works well in urban and rural areas
October 19, 2018 - Determining acid-neutralizing capacity for OTC antacids
October 19, 2018 - Males who spend more time taking care of kids have greater reproductive success
October 18, 2018 - Study to explore bioethics of brain organoids
October 18, 2018 - Environmental conditions may drive development of multiple sclerosis
October 18, 2018 - Genetically modifying zebrafish provides more accurate disease models
October 18, 2018 - Purdue Pharma, Eisai announce positive topline results from Phase 3 study of lemborexant
October 18, 2018 - 5 Strength-Training Mistakes to Avoid
October 18, 2018 - Immune system’s balancing act keeps bowel disease in check
October 18, 2018 - Anti-inflammatory drug effective for treating lymphedema symptoms | News Center
October 18, 2018 - Keeping Your Voice Young
October 18, 2018 - One-time universal screening recommended to tackle increase in hepatitis C
October 18, 2018 - Researchers to develop new stem cell-based strategies for treating vision disorders
October 18, 2018 - Detecting epigenetic signature may help people stay ahead of inflammatory bowel disease
October 18, 2018 - Understanding AFib: Slowing down the dancing heart
October 18, 2018 - Using NMR to Reduce Fraud
October 18, 2018 - New automated model identifies dense breast tissue in mammograms
October 18, 2018 - Mysterious polio-like illness baffles medical experts while frightening parents
October 18, 2018 - Cases of Acute Flaccid Myelitis on the rise across U.S.
October 18, 2018 - Dietary fiber reduces brain inflammation during aging
October 18, 2018 - New tool could help prioritize recovery efforts for the poorest hit by natural disasters
October 18, 2018 - Hundreds of dietary supplements shown to contain unapproved drugs
October 18, 2018 - Active Pharmaceuticals ID’d in >700 Dietary Supplements
October 18, 2018 - Cell death protein also damps inflammation
October 18, 2018 - AI pathology diagnostic tool developed using deep learning technology from Olympus
October 18, 2018 - Health Highlights: Oct. 15, 2018
October 18, 2018 - Largest study of ‘post-treatment controllers’ reveals clues about HIV remission
October 18, 2018 - Bad Blood in Silicon Valley: A conversation with John Carreyrou
October 18, 2018 - ANTRUK’s Annual Lecture sends out message on shortage of funds for antibiotic research
October 18, 2018 - NAM special publication outlines steps to ensure interoperability of health care systems
October 18, 2018 - Novel method uses just a drop of blood to monitor effect of lung cancer therapy
October 18, 2018 - New blood test could spare cancer patients from unnecessary chemotherapy
October 18, 2018 - Training young researchers to work with data volumes arising in the health sector
October 18, 2018 - New Metrohm IC method is reliable and convenient to use for zinc oxide assay
October 18, 2018 - Global AIDS, TB fight needs more money: health fund
October 18, 2018 - Understanding the forces that cause sports concussions
October 18, 2018 - Research points to new target for treating periodontitis
October 18, 2018 - New tool improves assessment of postpartum depression symptoms
October 18, 2018 - From Biopsy to Diagnosis
October 18, 2018 - Sexual harassment and assault linked to worse physical/mental health among midlife women
October 18, 2018 - Stumped by medical school? A Q&A with a learning specialist
October 18, 2018 - Report predicts life expectancy in 2040, Spain comes out on top
October 18, 2018 - Self-lubricating condoms may help raise condom usage
October 18, 2018 - Targeting immune checkpoints in microglia could reduce out-of-control neuroinflammation
October 18, 2018 - Study finds changes in antiepileptic drug metabolism during different trimesters of pregnancy
October 18, 2018 - Autonomic nervous system directly controls stem cell proliferation, study shows
October 18, 2018 - FDA Approves Talzenna (talazoparib) for gBRCAm HER2-Negative Locally Advanced or Metastatic Breast Cancer
October 18, 2018 - Sleeping Beauty technique helps identify genes responsible for NAFLD-associated liver cancer
October 18, 2018 - Many U.S. adults confused about primary care, study shows
October 18, 2018 - UC researcher focuses on light-mediated therapies to target breast cancer
October 18, 2018 - With philanthropic gifts, Stanford poised to make major advances in neurosciences | News Center
October 18, 2018 - Mice study shows antibiotics are not always necessary to cure sepsis
October 18, 2018 - Researchers discover why heart contractions are weaker in individuals with HCM
October 18, 2018 - Participation in organized sport during childhood may have long-term skeletal benefits
October 18, 2018 - Probiotic/antibiotic combination could eradicate drug-resistant bacteria
October 17, 2018 - More Socioeconomic Challenges for Hispanic Women With HIV
October 17, 2018 - 49,XXXXY syndrome – Genetics Home Reference
October 17, 2018 - Scientists uncover possible new causes of Tourette syndrome
October 17, 2018 - Girl undergoes unusual heart surgery after compassionate-use exemption | News Center
Chuck Norris Says MRI Dye Harmed Wife’s Brain, But Study Finds No Link

Chuck Norris Says MRI Dye Harmed Wife’s Brain, But Study Finds No Link

image_pdfDownload PDFimage_print

WEDNESDAY, Nov. 29, 2017 — Despite recent claims from actor Chuck Norris that a dye commonly used during MRI scans seriously sickened his wife, a new study finds no evidence to support such a link.

The substance in question is gadolinium. It’s a metal found in contrast agents that are injected into the body during an MRI scan, to enhance the quality of the images.

Earlier this month, Norris filed a lawsuit alleging that his wife fell ill after being exposed to gadolinium during MRI scans.

The suit says that Gena Norris was left weak, tired and suffering bouts of pain and burning sensations.

Doctors have been using gadolinium-based agents for 30 years — totaling more than 300 million doses, said Dr. Vikas Gulani, an associate professor of radiology at Case Western Reserve University in Cleveland.

But, Gulani explained, researchers have only recently discovered that trace amounts of the metal can be left behind in the brain.

In September, a U.S. Food and Drug Administration panel called for a warning to be added to the agents’ labels. The warning specifies that trace amounts of gadolinium may be retained in various organs, including the skin, bone and brain.

The big question remains, though: What, if any, are the harms?

The new findings, from a study of nearly 4,300 older adults, offer some reassurance. Researchers found no evidence that gadolinium exposure was related to faster mental decline over several years.

“The key issue is, if (this) substance deposits in trace amounts in the brain, are there any harms?” said Gulani, who was not involved in the new study.

He said this study is one of the first to address that question in a “meaningful way.”

“This gives us a critical piece of information,” Gulani said.

The report was based on 4,261 older adults who were part of a study looking at the natural course of “cognitive impairment” — milder problems with memory and thinking skills — and full-blown dementia.

At the outset, the participants had an average age of 72 and had no signs of impairment. About one-quarter had ever received a gadolinium-based agent during an MRI — typically within the past two to nine years.

Overall, there was no clear link between gadolinium exposure and older adults’ risk of cognitive decline over the next few years.

Nor was there any evidence that gadolinium exposure sped up people’s progression from milder impairment to dementia.

Dr. Robert McDonald, of the Mayo Clinic, in Rochester, Minn., led the study. He was scheduled to present the findings Wednesday at the annual meeting of the Radiological Society of North America, in Chicago. Research presented at meetings should be considered preliminary until published in a peer-reviewed journal.

“This study provides useful data that at the reasonable doses 95 percent of the population is likely to receive in their lifetime, there is no evidence at this point that gadolinium retention in the brain is associated with adverse clinical outcomes,” McDonald said in a news release from the meeting.

For now, the FDA says that gadolinium agents have only one known health risk: A “small subgroup” of kidney failure patients has developed a rare skin condition that causes a painful thickening of the skin.

“At this point,” Gulani said, “we are not aware of any harms from these agents being retained in the brain.”

Still, he added, the latest study does not rule out that possibility. There are still open questions — including whether gadolinium exposure could be related to other neurological issues, like movement problems.

Gadolinium-based agents help brighten tissues in MRI scans, and are considered an important part of getting accurate diagnoses — for everything from cancer, to heart conditions, to liver disease.

So, Gulani said, any theoretical risks from the agents have to be balanced against their proven benefits.

Still, there are cases where an MRI can be done without a contrast agent, Gulani noted. “It’s reasonable for patients to ask their doctor whether it’s needed or not,” he said.

Gulani helped craft the latest recommendations from the International Society of Magnetic Resonance in Medicine on using MRI contrast agents. They say that if a gadolinium-based agent is not necessary, it should be skipped.

“It’s just like with any other medication,” Gulani said. “If you don’t need it, don’t use it.”

More information

The FDA has more on gadolinium-based contrast agents.

© 2017 HealthDay. All rights reserved.

Posted: November 2017

Recommended for you

Tagged with:

About author

Related Articles