Download PDF PET scan of a human brain with Alzheimer’s disease. Credit: public domain A new link between diminished input from dopamine-firing cells deep inside the brain and the ability to form new memories could be crucial in detecting the earliest signs of Alzheimer’s disease. Scientists from the National Institute for Health Research (NIHR) Sheffield […]Continue Reading ...
Download PDF April 19, 2018 In the current issue of Cardiovascular Innovations and Applications (Volume 2, Number 4, 2018, pp 447-449(3); DOI: https://doi.org/10.15212/CVIA.2017.0028, Niya Mileva, Medical University of Sofia, Sofia, Bulgaria and other researchers from Poland and Italy present a case study of misdiagnosed aortic intramural hematoma and the role of intravascular ultrasound imaging in […]Continue Reading ...
Download PDF April 18, 2018 In the wrestling match with cancer, chemoimmunotherapy is the new strong arm, and it is building muscle with a nanodisc disguised as “good cholesterol.” Researchers at the University of Michigan Rogel Cancer Center designed this new delivery system – a drug hidden in a nanodisc – to increase the number […]Continue Reading ...
Download PDF April 17, 2018 Most of the roughly 15.5 million cancer survivors in the U.S. receive chemotherapy, and roughly 65 percent develop some degree of the chemotherapy-induced nerve damage known as peripheral neuropathy. Peripheral neuropathy simply means nerves outside of the brain and spinal cord are affected, and symptoms include numbness and tingling in […]Continue Reading ...
Download PDF April 18, 2018 By tracking individual microbubbles, high-resolution images can be taken with conventional ultrasound scanners. Thanks to a new method of analyzing ultrasound images, conventional scanners can be used for generating high-res images of blood vessels in tumors. This approach makes it easier to distinguish between different types of tumors, and it […]Continue Reading ...
Download PDF IU professor Sharlene Newman and senior scientist Hu Cheng in the IU Bloomington Imaging Research Facility. Credit: Eric Rudd, Indiana University A study led by Indiana University on neurochemical changes associated with alcohol addiction found that the neurotransmitter glutamate plays a role in some alcohol cravings. Alcohol dependence and alcohol use disorders occur […]Continue Reading ...
Download PDF April 19, 2018 Existing microscopy-based methods of detecting apoptosis, such as TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling), have limited quantitative capabilities due to insufficient signal-to-noise ratios. Researchers at the National Cancer Institute and National Cancer Institute-Frederick have addressed this issue via development of a highly specific apoptosis assay designed for immunofluorescence microscopy […]Continue Reading ...
Download PDF April 19, 2018 Memory T cells are a critical element of our immune system’s historical archive. To prevent repeat infections, these cells retain a record of germs they’ve fought before. But for all their importance, the origins of memory T cells have remained a mystery. Now, a new study from the laboratory of […]Continue Reading ...
Download PDF April 17, 2018 Scientists have just discovered a new mechanism by which HIV evades the immune system, and which shows precisely how the virus avoids elimination. The new research shows that HIV targets and disables a pathway involving a number of biological molecules that are key in blocking viral activity and clearing infection. […]Continue Reading ...
Download PDF April 18, 2018 There are no laboratory tests to diagnose migraines, depression, bipolar disorder and many other ailments of the brain. Doctors typically gauge such illnesses based on self-reported symptoms and behavior. Now, a new study shows that a kind of brain scan called functional connectivity MRI (fcMRI) – which shows how brain […]Continue Reading ...
Download PDF April 18, 2018 Despite universal newborn screening that detects the presence of sickle cell trait (SCT), only 16 percent of Americans with SCT know their status. To address this issue, in Ohio, in-person education is offered to caregivers of referred infants with SCT. “Most people do not know their sickle cell trait status. […]Continue Reading ...
Download PDF News Release Friday, April 13, 2018 Preliminary NIH study shows increased levels of beta-amyloid. Losing just one night of sleep led to an immediate increase in beta-amyloid, a protein in the brain associated with Alzheimer’s disease, according to a small, new study by researchers at the National Institutes of Health. In Alzheimer’s disease, […]Continue Reading ...
Download PDF April 18, 2018 Calcific aortic valve disease (CAVD) – a disease that leaves the aortic valve stiff and calcified, preventing blood flow from the heart into the aorta – affects one quarter of the U.S. population aged 65 and over. There is no pharmacological treatment for CAVD. Without an invasive valve replacement surgery, […]Continue Reading ...
Download PDF April 17, 2018 Many chemotherapeutics act by damaging the DNA. Since cancer cells divide more often than most normal cells, they react more sensitive to DNA damaging agents. One exception are oocytes. To prevent birth defects they initiate a cellular death program if DNA damage is detected. This process, called apoptosis, is triggered […]Continue Reading ...
Download PDF FDA Approves Crysvita (burosumab-twza) for X-Linked Hypophosphatemia April 17, 2018 — The U.S. Food and Drug Administration today approved Crysvita (burosumab), the first drug approved to treat adults and children ages 1 year and older with x-linked hypophosphatemia (XLH), a rare, inherited form of rickets. XLH causes low levels of phosphorus in the […]Continue Reading ...
- Detecting diminished dopamine-firing cells inside brain could reveal earliest signs of Alzheimer’s
- Case study shows how intravascular ultrasound imaging helps detect acute aortic syndrome
- Research reveals new mechanism by which HIV evades the immune system
- Nanodisc-delivered cancer treatment helps eliminate tumors
- Functional connectivity MRI could help detect brain disorders and diseases
- Finding better way to quantify neuropathy symptoms and treatment efficacy
- Study examines effectiveness of caregiver education about sickle cell trait
- High-resolution images of tumor vasculature using new technology
- Lack of sleep may be linked to risk factor for Alzheimer’s disease
- Study finds neurotransmitter may play a role in alcohol relapse, addiction
- Researchers build molecular networks of calcific aortic valve disease
- Researchers develop highly specific apoptosis assay for pharmacodynamic analyses of tumor specimens
- Scientists decipher mechanism of chemotherapy induced female infertility
- New insight may allow researchers to design drugs that improve immune responses to vaccines
- FDA Approves Crysvita (burosumab-twza) for X-Linked Hypophosphatemia
- Researchers uncover origin of virus-fighting plasma B cells
- Study finds no evidence of lower intelligence in young children who had anesthesia
- Baboons break out of research facility briefly
- Study shows how deployment time increases risk of suicide attempt in soldiers
- Specific odors from malaria infected individuals attract more mosquitoes