Breaking News
July 23, 2018 - Yeast species used in biotechnology, food industries causes drug-resistant yeast infections
July 23, 2018 - Breath analyses may help detect pancreatic cancer earlier, study shows
July 23, 2018 - Study reports data on dementia prevalence in sexual minority older adults
July 23, 2018 - Children of mothers with type 1 diabetes at greater risk of being overweight
July 23, 2018 - Deep brain stimulation found to improve diabetes symptoms
July 23, 2018 - New breeding technologies could enhance shape, size, color, and health benefits of produce
July 23, 2018 - Pfizer announces FDA approval of biosimilar to Neupogen
July 23, 2018 - Key questions to consider for sustainable management of environmental risks in Europe
July 23, 2018 - Vaxart Announces Publication of the Phase 1 Results of its Oral Norovirus Tablet Vaccine in Journal of Clinical Investigation Insight
July 23, 2018 - Joslin researchers report excessive fetal growth despite well-controlled type 1 diabetes
July 23, 2018 - Former inmates more likely to die of opioid overdose after prison release
July 23, 2018 - New study offers robust insights into under-treatment of women with heart attacks
July 23, 2018 - Doctors’ ‘gut feelings’ play key role in medical decision making, finds study
July 23, 2018 - Tooth enamel that regrows? Researcher says revolutionary gel could make it possible
July 23, 2018 - ECU researchers develop world’s first blood test that detects melanoma in its early stages
July 23, 2018 - Researchers explore future of houseplants as functional sirens of home health
July 23, 2018 - No Outcome Differences Based on Anesthesia Team Make-Up
July 23, 2018 - Getting to the heart of congenital cardiac defects
July 23, 2018 - Healthy behaviors are not effective in preventing gestational diabetes in obese women
July 23, 2018 - Top of Teachers’ To-Do List: Focus on the Positives
July 23, 2018 - LDL quality is a novel, modifiable cardiovascular risk marker
July 22, 2018 - Researchers identify enzyme as potential new drug target for blood disorders
July 22, 2018 - Research shows that neurons can encode more than one signal at a time
July 22, 2018 - Exposure to secondhand smoke increases the risk of stillbirth
July 22, 2018 - Skin conditions by the numbers
July 22, 2018 - Brain tumour chemotherapy now available to even more NHS patients
July 22, 2018 - Researchers find mugwort pollen as major source of airborne endotoxins
July 22, 2018 - Occupational safety and health at workplace
July 22, 2018 - Pfizer And Lilly Announce Positive Top-Line Results From Phase 3 Trial Of Tanezumab For The Treatment Of Osteoarthritis (OA) Pain
July 22, 2018 - Early supper associated with lower risk of breast and prostate cancer
July 22, 2018 - Survey results identify major inequalities in acute stroke treatment across Europe
July 22, 2018 - Researchers discover promising treatment for genetic form of autism spectrum disorder
July 22, 2018 - Prenatal Depression More Common in Young Moms Today
July 22, 2018 - What helps adults with autism get and keep a job?
July 22, 2018 - Pediatric NEXUS Head CT DI guides selective imaging decisions in blunt trauma patients
July 22, 2018 - Novel tool predicts genes that cause disease due to production of truncated proteins
July 22, 2018 - AHA: Vaping Tied to Blood Clots — in Mice
July 22, 2018 - Study finds therapy dogs effective in reducing symptoms of ADHD
July 22, 2018 - Scientists find reason why malarial parasites are faster than immune cells
July 22, 2018 - Researchers gain more insight into how FUS protein causes ALS and FTLD
July 22, 2018 - Frequency of joint replacements halved in rheumatoid arthritis patients between 1997-2010
July 22, 2018 - QUT researcher highlights growing impact of non-prescription antibiotics supply in pharmacies
July 22, 2018 - UK health communication researcher seeks solutions for disposing leftover medicine
July 22, 2018 - Pfizer Initiates Pivotal Phase 3 Program for Investigational Hemophilia B Gene Therapy Fidanacogene Elaparvovec
July 22, 2018 - Mutation discovered to protect against Alzheimer’s disease in mice
July 22, 2018 - Researchers reveal how patients in urban areas develop multiple, long-term conditions
July 22, 2018 - Replacing conventional cancer treatment with complementary therapy linked to increased risk of death
July 22, 2018 - Study uncovers molecular key for delaying progression of multiple sclerosis
July 22, 2018 - Availability of athletic trainer in high school reduces injury rates in girls’ sports, shows study
July 22, 2018 - FDA Approves Krintafel (tafenoquine) for the Radical Cure of Plasmodium vivax Malaria
July 22, 2018 - Novel nuclear medicine probe will help assess new drugs for neurodegenerative diseases
July 22, 2018 - Physical activity even during exposure to air pollution can reduce risk of heart attack
July 22, 2018 - Scientists discover protein regulator of myelin production
July 22, 2018 - Sleep disturbances associated with higher dementia risk
July 22, 2018 - Scientists move one step further in developing eye drops to treat age-related macular degeneration
July 22, 2018 - Five-Year Stroke Rates Lower After PCI Versus CABG
July 21, 2018 - Alopecia areata – Genetics Home Reference
July 21, 2018 - Study identifies overdose risk factors in youth with substance use disorders
July 21, 2018 - Drug in clinical trials for Parkinson’s disease offers hope for treating heart failure
July 21, 2018 - Coupling free malaria tests with diagnosis-dependent vouchers can improve rational use of ACTs
July 21, 2018 - Sweetness depends on molecular interactions between specific sugars and water in saliva
July 21, 2018 - Muscle fitness is strongly associated with improved rate of ageing in the brain
July 21, 2018 - Resetting E-Prescriptions for Opioids Helps Curb Use: Study
July 21, 2018 - Overuse of antibiotics not what the doctor ordered
July 21, 2018 - Bundled-payment system did not lower costs for serious medical conditions, shows study
July 21, 2018 - Therapy dogs found to be effective in reducing ADHD symptoms in children
July 21, 2018 - Could rotating multiple therapists better treat PTSD patients?
July 21, 2018 - Binge drinking impairs working memory in adolescent brain
July 21, 2018 - Dying at home could be beneficial for terminally ill cancer patients and their relatives
July 21, 2018 - Researchers identify subtypes of retinal ganglion cells using single-cell RNA sequencing
July 21, 2018 - Study uncovers opportunities to reduce death by suicide among cancer patients
July 21, 2018 - Genetic sequencing reveals new clues to aggressiveness of prostate cancer
July 21, 2018 - BioSight Launches a Phase 2b Clinical Trial of BST-236 as a First-Line Treatment of Acute Myeloid Leukemia
July 21, 2018 - First major study comparing robotic to open surgery published in The Lancet
July 21, 2018 - ADHD medications may fail to improve cognition in healthy college students, study shows
July 21, 2018 - Intervention program that includes a personalized app could benefit teens with suicidal thoughts
July 21, 2018 - Researchers identify new compound that protects against neurodegeneration
July 21, 2018 - Gene therapy may hold potential to treat people with spinal cord injuries
July 21, 2018 - FDA Approves Nivestym (filgrastim-aafi), a Biosimilar to Neupogen
July 21, 2018 - Surgeons have substantial impact on genetic testing in breast cancer patients who need it
Alpha brain wave frequency could help measure individual’s vulnerability to pain, study finds

Alpha brain wave frequency could help measure individual’s vulnerability to pain, study finds

image_pdfDownload PDFimage_print

The frequency of alpha brain waves can be used as a measure of an individual’s vulnerability to developing and experiencing pain, researchers at the University of Birmingham in the UK and University of Maryland in the US have discovered.

The personal experience of pain is highly variable among individuals, even in instances where the underlying injury is assessed to be identical.

Previous research has found some genetic factors influence pain susceptibility, but methods to accurately predict pain level consequent to medical intervention such as chemotherapy or surgery are lacking.

The objective of this study was to see if, from the resting brain activity of a healthy individual, it was possible to predict how much pain they would report once prolonged pain had been induced.  

The researchers induced the pain using a capsaicin paste – an ingredient found in hot chili peppers – to study participants’ left forearm and then heated it.  Topical capsaicin exposure induces ‘robust thermal hyperalgesia’ – a common symptom in chronic pain. All 21 participants in the study were induced in a state of prolonged pain for around an hour.

Using an electroencephalogram (EEG) – a non-invasive test used to find problems related to the electrical activity of the brain – the researchers found that across all 21 study participants, those who had a slower frequency of alpha brain waves recorded before the pain, reported being in much more pain than those who had a fast frequency of alpha brain waves.

The researchers also recorded the activity of alpha brain waves during the experience of pain, and if alpha frequency increased (relative to the no-pain condition) the individuals reported to be in less pain than when alpha pain decreased.

Co-senior author Dr Ali Mazaheri, of the University of Birmingham’s Center for Human Brain Health, said: “Here we observe that an individual’s alpha frequency can be used as a measure of an individual’s predisposition to developing pain.  

“This has a direct relevance to understanding what makes an individual prone to chronic pain after a medical intervention, such as surgery or chemotherapy.

“Potentially this means we could be able to identify which individuals are more likely to develop pain as a result of a medical procedure and take steps early on in formulating treatment strategies in patients likely to be predisposed to developing chronic pain.”

Dr David Seminowicz and Andrew Furman, of the University of Maryland in the US, were also authors of the report.

Andrew Furman said: “Alpha frequency has been found to be slower in individuals who have experienced chronic pain.  So the fact we observed that the slowing down of alpha activity as a result of pain correlated with the intensity of an individual’s pain report was not that unexpected.

“What was very surprising though, was that prior to the pain – that is pain-free alpha frequency – could predict how much pain individuals would experience.

“This would suggest that it could be that the slowing of alpha activity in the chronic pain patients, isn’t because of the pain, but rather these individuals had slow alpha frequency to begin with, and as such were more prone or vulnerable to developing pain.”

Source:

https://www.birmingham.ac.uk/news/latest/2018/03/brain-waves-pain-university-birmingham.aspx

Tagged with:

About author

Related Articles