Breaking News
January 24, 2019 - FDA authorizes marketing of new test to aid in the diagnosis of M. gen. infections
January 24, 2019 - Health Tip: Simple CPR – Drugs.com MedNews
January 24, 2019 - Diabetes in America, 3rd Edition
January 24, 2019 - Bangladesh ‘Tree Man’ returns to hospital as condition worsens
January 24, 2019 - Costs of gun-related hospitalizations, readmissions examined in study
January 24, 2019 - Good health literacy linked to better adherence to blood pressure medications among Hispanics
January 24, 2019 - Only a minority of patients in the U.S. with type 1 diabetes achieve treatment goals
January 24, 2019 - High fat reduces efficiency of the immune system to fight infectious disease
January 24, 2019 - FDA grants clearance to Hologic’s assay for detection of common sexually transmitted infections
January 24, 2019 - Study highlights need for reliable therapeutic targets for prevention, treatment of cardiovascular diseases
January 24, 2019 - Next step toward replacement therapy in type 1 diabetes
January 24, 2019 - “Scientific serendipity” identifies link between type of RNA and autism
January 24, 2019 - Trump Zeroes In On Surprise Medical Bills In White House Chat With Patients, Experts
January 24, 2019 - Unique form of chronic sinusitis found in older patients
January 24, 2019 - NUS researchers make muscle recovery easier for patients with ingenious medical device
January 24, 2019 - Specific cognitive deficits found in individuals with spinal cord injury
January 24, 2019 - An essential reference for diagnostic ultrasonography and biopsy of the thyroid gland
January 24, 2019 - Proteus Digital Health Launches Digital Oncology Medicines to Improve Patient Outcomes
January 24, 2019 - Study looking to prevent type 1 diabetes follows children into adolescence
January 24, 2019 - Nice doctors make a difference
January 23, 2019 - Blood vessel discovery could advance our knowledge of osteoporosis
January 23, 2019 - New esophageal cancer test uses genetic biomarkers to detect changes in esophagal cells
January 23, 2019 - Study evaluates first-ever Robotic Visualization System for neurosurgery
January 23, 2019 - Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures
January 23, 2019 - Both educational level and occupational orientation predict mother’s smoking during pregnancy
January 23, 2019 - How to (gently) get your child to brush their teeth
January 23, 2019 - Short-term hospital readmissions for gun injuries cost $86 million a year | News Center
January 23, 2019 - New certified reference material for testing residual solvents in cannabis
January 23, 2019 - Gene-edited chickens could prevent future flu pandemic
January 23, 2019 - Cardiovascular disease risk begins even before birth
January 23, 2019 - Younger patients receiving kidney transplant more likely to live longer, shows data
January 23, 2019 - Skin samples hold early signs of prion disease, research suggests
January 23, 2019 - Researchers discover how body initiates repair mechanisms that limits damage to myelin sheath
January 23, 2019 - Fecal transplant from certain donors better than others
January 23, 2019 - Risk for Uninsurance in AMI Patients Reduced With Medicaid Expansion
January 23, 2019 - Readmissions reduction program may be associated with increase in patient-level mortality
January 23, 2019 - Fostering translation and communication in medicine and beyond
January 23, 2019 - To Fight Fatty Liver, Avoid Sugary Foods and Drinks
January 23, 2019 - TPU scientists develop new implants that double the rate of bone lengthening in kids
January 23, 2019 - New sessions at Pittcon 2019
January 23, 2019 - Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum
January 23, 2019 - Opioid overdose patients can be safely discharged an hour after administration of naloxone
January 23, 2019 - Scientists find bacterial extracellular vesicles in human blood
January 23, 2019 - Researchers use modified type of flu virus to develop new therapies for prostate cancer
January 23, 2019 - Researchers gain new insights into development of necrotizing enterocolitis in preemies
January 23, 2019 - Medical expert advises people with epilepsy not to stockpile medicines
January 23, 2019 - CDC study explores link between smoking and clinical outcomes of assisted reproductive technology
January 23, 2019 - Study outlines research priorities for improving pediatric patient care and safety
January 23, 2019 - Bedfont to exhibit NObreath FeNO monitor at Arab Health 2019
January 23, 2019 - Nicotinamide riboside supplementation confers significant physiological benefits to mothers and offspring
January 23, 2019 - Increasing temperatures may help preserve crop nutrition
January 23, 2019 - Many Oncologists in the Dark About LGBTQ Health Needs
January 23, 2019 - Epigenetic change causes fruit fly babies to inherit diet-induced heart disease
January 23, 2019 - Erasing memories could reduce relapse rates among drug addicts
January 23, 2019 - African Americans who smoke cigarettes are more likely to develop peripheral artery disease
January 23, 2019 - Unique data combination helps FinnGen researchers to fund links between genetic factors and health
January 23, 2019 - Parents’ mental health problems associated with reactive attachment disorder in children
January 23, 2019 - Graphene Flagship project studies impact of graphene and related materials on our health
January 23, 2019 - The connection between the Pope and contraceptive pills
January 23, 2019 - Prior dengue infection could protect children from symptomatic Zika
January 23, 2019 - Previous dengue virus infection associated with protection from symptomatic Zika
January 23, 2019 - VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance
January 23, 2019 - The Tiny Camera That Could Revolutionize Cardiovascular Surgery
January 23, 2019 - Peptide isolated from soil fungi has antitumor and antibacterial properties
January 23, 2019 - TGen identifies polio-like virus as potential cause of Acute Flaccid Myelitis outbreak
January 23, 2019 - Migrants and refugees do not bring disease and are at greater health risk themselves says WHO
January 23, 2019 - Examing the effects of menopause in workplace
January 23, 2019 - Enemy number 1 – Air pollution and climate change top of WHO agenda
January 23, 2019 - Two Positive Phase III studies of Tafenoquine for the Radical Cure of Plasmodium vivax Malaria Published in The New England Journal of Medicine
January 23, 2019 - World Trade Center responders at increased risk for head and neck cancers
January 23, 2019 - Low-sugar diet leads to significant improvement in nonalcoholic fatty liver disease in boys
January 23, 2019 - Chaos in bodily regulation can optimize our immune system, finds study
January 23, 2019 - Short, text-based exercises can increase happiness for adults recovering from substance use disorders
January 23, 2019 - Body size may have greater influence on women’s lifespan than men
January 23, 2019 - Groundbreaking tool helps visualize neuronal activity with near-infrared light
January 23, 2019 - Prior dengue immunity in children may be protective against symptomatic Zika
January 23, 2019 - Holocaust survivors with PTSD and their offspring exhibit more unhealthy behavior patterns
January 23, 2019 - Scientists discover new genetic mutations causing inherited deaf-blindness
January 23, 2019 - UC team designs new naloxone-dispensing smart device
January 23, 2019 - Torrent Pharmaceuticals Limited Issues Voluntary Nationwide Recall of Losartan Potassium Tablets, USP and Losartan Potassium and Hydrochlorothiazide Tablets, USP
Positive interventions in sepsis management raise key questions about E. coli reduction targets

Positive interventions in sepsis management raise key questions about E. coli reduction targets

image_pdfDownload PDFimage_print

Sepsis detection success raises important questions about E. coli reduction targets

Work to improve sepsis detection, supported by the Bevan Commission Academy, suggests that hospitals may be measuring the wrong metrics for success

A sepsis awareness and management program has demonstrated overall success in terms of improved sepsis detection, but has led to an increase in the number of E. coli blood stream infection cases presented, calling into question the targets used by Welsh Health Boards and set by the Welsh Government in the UK.

Sepsis is a serious complication of an infection, which can lead to multiple organ failure or even death. Hywel Dda University Health Board has been proactive in its adoption of sepsis diagnosis measures, working closely with the Public Health Wales initiative 1000 Lives, led by RRAILS Lead Chris Hancock, to improve detection and management.

A Bevan Exemplar program was established in the Hywel Dda University Health Board area with the goal to reduce healthcare-associated infections. The program was rolled out in primary and secondary care institutions across West Wales in 2016 and was originally designed to address E. coli bacteraemia reduction targets. Bevan Exemplars, supported by the Bevan Commission, are provided with expert mentoring to pursue projects which improve NHS Wales’ health outcomes, patient experience or resource efficiency.

The architects of the program, Dr Mike Simmons and Mrs Sharon Daniels, found that positive interventions in sepsis management caused the E. coli bacteraemia increases. The sepsis awareness team in Hywel Dda University Health Board was found to be succeeding in their early detection of sepsis and were taking more blood cultures than in previous years, giving an increase in presentations of E. coli bacteraemia and other organisms.

Fifteen years’ worth of data (totaling 200,000 blood culture sets) was analyzed, which showed a recent increase in the number of E. coli presentations, correlating with improved sepsis management compliance.

The team behind the program has made recommendations to the bodies setting infection reduction targets. These recommendations include that alternative metrics, such as the ratio of positive to negative samples and analyzing urine samples, may provide a more accurate measure of success instead of the existing E. coli reduction target.

Dr Mike Simmons, Bevan Exemplar and Public Health Wales Microbiology, Carmarthen, said:

It was immensely beneficial to have access to the Bevan Commission and our mentor and Bevan Commissioner Professor John Wyn Owen (former Director of the NHS in Wales), who was able to provide very valuable expertise, which helped us to develop our thinking. Although our sensitive sepsis detection program failed against the E. coli reduction target, it has contributed to improving sepsis diagnosis and management overall. This work led us to consider alternative measures which demonstrate an improvement in quality of services, leading to major waste reduction in the NHS.

Siôn Charles, Deputy Director, Bevan Commission, said:

The Bevan Commission Academy has been designed to strengthen leadership and innovation in health, in Wales and beyond. This particular case study demonstrates the importance of providing the time and support needed for future health leaders to innovate, which often involves failing fast or finding new ways to frame challenges in the NHS. In this case, an initial failure to meet E. coli reduction targets has opened up an important debate about the usefulness of these metrics, and points to success in other important areas such as sepsis detection.

The full findings have been published in the Journal of Hospital Infection.

The Bevan Commission, hosted and supported by Swansea University, brings together a group of internationally renowned experts to provide independent advice on health and care to the Welsh Government and leaders across Wales, the UK and worldwide.

Source:

http://www.swansea.ac.uk/

Tagged with:

About author

Related Articles