Breaking News
January 24, 2019 - FDA authorizes marketing of new test to aid in the diagnosis of M. gen. infections
January 24, 2019 - Health Tip: Simple CPR – Drugs.com MedNews
January 24, 2019 - Diabetes in America, 3rd Edition
January 24, 2019 - Bangladesh ‘Tree Man’ returns to hospital as condition worsens
January 24, 2019 - Costs of gun-related hospitalizations, readmissions examined in study
January 24, 2019 - Good health literacy linked to better adherence to blood pressure medications among Hispanics
January 24, 2019 - Only a minority of patients in the U.S. with type 1 diabetes achieve treatment goals
January 24, 2019 - High fat reduces efficiency of the immune system to fight infectious disease
January 24, 2019 - FDA grants clearance to Hologic’s assay for detection of common sexually transmitted infections
January 24, 2019 - Study highlights need for reliable therapeutic targets for prevention, treatment of cardiovascular diseases
January 24, 2019 - Next step toward replacement therapy in type 1 diabetes
January 24, 2019 - “Scientific serendipity” identifies link between type of RNA and autism
January 24, 2019 - Trump Zeroes In On Surprise Medical Bills In White House Chat With Patients, Experts
January 24, 2019 - Unique form of chronic sinusitis found in older patients
January 24, 2019 - NUS researchers make muscle recovery easier for patients with ingenious medical device
January 24, 2019 - Specific cognitive deficits found in individuals with spinal cord injury
January 24, 2019 - An essential reference for diagnostic ultrasonography and biopsy of the thyroid gland
January 24, 2019 - Proteus Digital Health Launches Digital Oncology Medicines to Improve Patient Outcomes
January 24, 2019 - Study looking to prevent type 1 diabetes follows children into adolescence
January 24, 2019 - Nice doctors make a difference
January 23, 2019 - Blood vessel discovery could advance our knowledge of osteoporosis
January 23, 2019 - New esophageal cancer test uses genetic biomarkers to detect changes in esophagal cells
January 23, 2019 - Study evaluates first-ever Robotic Visualization System for neurosurgery
January 23, 2019 - Scientists reveal new mechanism that could lead to specific treatment of strokes and seizures
January 23, 2019 - Both educational level and occupational orientation predict mother’s smoking during pregnancy
January 23, 2019 - How to (gently) get your child to brush their teeth
January 23, 2019 - Short-term hospital readmissions for gun injuries cost $86 million a year | News Center
January 23, 2019 - New certified reference material for testing residual solvents in cannabis
January 23, 2019 - Gene-edited chickens could prevent future flu pandemic
January 23, 2019 - Cardiovascular disease risk begins even before birth
January 23, 2019 - Younger patients receiving kidney transplant more likely to live longer, shows data
January 23, 2019 - Skin samples hold early signs of prion disease, research suggests
January 23, 2019 - Researchers discover how body initiates repair mechanisms that limits damage to myelin sheath
January 23, 2019 - Fecal transplant from certain donors better than others
January 23, 2019 - Risk for Uninsurance in AMI Patients Reduced With Medicaid Expansion
January 23, 2019 - Readmissions reduction program may be associated with increase in patient-level mortality
January 23, 2019 - Fostering translation and communication in medicine and beyond
January 23, 2019 - To Fight Fatty Liver, Avoid Sugary Foods and Drinks
January 23, 2019 - TPU scientists develop new implants that double the rate of bone lengthening in kids
January 23, 2019 - New sessions at Pittcon 2019
January 23, 2019 - Insilico to present latest findings in AI for Drug Discovery at 3rd Annual SABPA FTD Forum
January 23, 2019 - Opioid overdose patients can be safely discharged an hour after administration of naloxone
January 23, 2019 - Scientists find bacterial extracellular vesicles in human blood
January 23, 2019 - Researchers use modified type of flu virus to develop new therapies for prostate cancer
January 23, 2019 - Researchers gain new insights into development of necrotizing enterocolitis in preemies
January 23, 2019 - Medical expert advises people with epilepsy not to stockpile medicines
January 23, 2019 - CDC study explores link between smoking and clinical outcomes of assisted reproductive technology
January 23, 2019 - Study outlines research priorities for improving pediatric patient care and safety
January 23, 2019 - Bedfont to exhibit NObreath FeNO monitor at Arab Health 2019
January 23, 2019 - Nicotinamide riboside supplementation confers significant physiological benefits to mothers and offspring
January 23, 2019 - Increasing temperatures may help preserve crop nutrition
January 23, 2019 - Many Oncologists in the Dark About LGBTQ Health Needs
January 23, 2019 - Epigenetic change causes fruit fly babies to inherit diet-induced heart disease
January 23, 2019 - Erasing memories could reduce relapse rates among drug addicts
January 23, 2019 - African Americans who smoke cigarettes are more likely to develop peripheral artery disease
January 23, 2019 - Unique data combination helps FinnGen researchers to fund links between genetic factors and health
January 23, 2019 - Parents’ mental health problems associated with reactive attachment disorder in children
January 23, 2019 - Graphene Flagship project studies impact of graphene and related materials on our health
January 23, 2019 - The connection between the Pope and contraceptive pills
January 23, 2019 - Prior dengue infection could protect children from symptomatic Zika
January 23, 2019 - Previous dengue virus infection associated with protection from symptomatic Zika
January 23, 2019 - VISTA checkpoint implicated in pancreatic cancer immunotherapy resistance
January 23, 2019 - The Tiny Camera That Could Revolutionize Cardiovascular Surgery
January 23, 2019 - Peptide isolated from soil fungi has antitumor and antibacterial properties
January 23, 2019 - TGen identifies polio-like virus as potential cause of Acute Flaccid Myelitis outbreak
January 23, 2019 - Migrants and refugees do not bring disease and are at greater health risk themselves says WHO
January 23, 2019 - Examing the effects of menopause in workplace
January 23, 2019 - Enemy number 1 – Air pollution and climate change top of WHO agenda
January 23, 2019 - Two Positive Phase III studies of Tafenoquine for the Radical Cure of Plasmodium vivax Malaria Published in The New England Journal of Medicine
January 23, 2019 - World Trade Center responders at increased risk for head and neck cancers
January 23, 2019 - Low-sugar diet leads to significant improvement in nonalcoholic fatty liver disease in boys
January 23, 2019 - Chaos in bodily regulation can optimize our immune system, finds study
January 23, 2019 - Short, text-based exercises can increase happiness for adults recovering from substance use disorders
January 23, 2019 - Body size may have greater influence on women’s lifespan than men
January 23, 2019 - Groundbreaking tool helps visualize neuronal activity with near-infrared light
January 23, 2019 - Prior dengue immunity in children may be protective against symptomatic Zika
January 23, 2019 - Holocaust survivors with PTSD and their offspring exhibit more unhealthy behavior patterns
January 23, 2019 - Scientists discover new genetic mutations causing inherited deaf-blindness
January 23, 2019 - UC team designs new naloxone-dispensing smart device
January 23, 2019 - Torrent Pharmaceuticals Limited Issues Voluntary Nationwide Recall of Losartan Potassium Tablets, USP and Losartan Potassium and Hydrochlorothiazide Tablets, USP
Home-based exercise program found ineffective for patients with peripheral artery disease

Home-based exercise program found ineffective for patients with peripheral artery disease

image_pdfDownload PDFimage_print

A home-based exercise program, consisting of wearable devices and telephone coaching, did not improve walking ability for patients with peripheral artery disease, according to a new Northwestern Medicine study.

The study, published in the Journal of the American Medical Association (JAMA), was led by Mary McDermott, MD, ’92 GME, the Jeremiah Stamler Professor of Medicine at Northwestern University Feinberg School of Medicine.

Peripheral artery disease (PAD), which affects up to 20 percent of people older than 60, is a condition in which blockages in blood vessels in the legs lead to pain or weakness when walking.

Previously, research has demonstrated that supervised treadmill exercise significantly improves walking ability in people with PAD, and clinical guidelines currently recommend such a program as first-line therapy. Home walking exercise activity also improves walking ability in PAD and is considered a reasonable alternative to supervised exercise by clinical guidelines — but effective interventions to date have included regular visits to the medical center.

However, regular visits to a medical center for supervised exercise can be burdensome and most patients decline to participate in supervised exercise. As such, investigators have been eager to explore more convenient interventions that would allow for at-home exercise.

“There is growing interest in using wearable activity monitors to motivate people to increase walking exercise and activity,” McDermott said.

In the current trial, investigators designed a home-based exercise program that included a wearable activity monitor and regular telephone calls from a coach. The randomized trial, which is the first of its kind, enrolled 200 participants from Northwestern, New York University and the University of Minnesota. Half of the participants received the exercise intervention, while the control group received no intervention. The primary outcome was the change in distance walked over a six-minute period.

At nine months follow-up, the investigators found there was no significant difference in walking ability between the two groups. Furthermore, the exercise intervention was associated with worsened pain that interfered with daily activities. The authors suggest that this may be because participants’ attempts to exercise resulted in greater ischemic leg symptoms, while the control group may have limited their activity to avoid symptoms, reducing pain.

The findings do not support the use of home-based exercise with wearable devices and telephone coaching without periodic on-site visits, the authors conclude.

“Further research is needed to identify home-based exercise interventions for people with PAD that are effective but are not overly burdensome — i.e., do not require frequent visits to the medical center,” McDermott said.

In January, Feinberg was awarded an American Heart Association (AHA) Strategically Focused Research Network Center dedicated to calf muscle pathology and disability in PAD. The center, led by McDermott, will conduct three studies to establish ischemia-related calf muscle pathological characteristics, with the eventual goal of identifying therapeutic interventions to prevent mobility loss in PAD.

Tagged with:

About author

Related Articles