Breaking News
January 21, 2019 - FDA Advisory Committee Votes on Zynquista (sotagliflozin) as Treatment for Adults with Type 1 Diabetes
January 21, 2019 - The causes and complications of snoring
January 21, 2019 - Placenta adapts and compensates when pregnant mothers have poor diets or low oxygen
January 21, 2019 - New implant could restore the transmission of electrical signals in injured central nervous system
January 21, 2019 - Rapid-acting fentanyl test strips found to be effective at reducing overdose risk
January 21, 2019 - Coronary Artery Calcium May Help Predict CVD in South Asians
January 21, 2019 - The mystery of the super-ager
January 21, 2019 - Scientists develop smart microrobots that can change shape depending on their surroundings
January 21, 2019 - Keep Moving to Keep Brain Sharp in Old Age
January 21, 2019 - Despite progress, gay fathers and their children still structurally stigmatized
January 21, 2019 - Merck recognized with 2018 Life Science Industry Award for best use of social media
January 21, 2019 - Coeur Wallis equips the canton of Valais with 260 SCHILLER defibrillators
January 21, 2019 - Scientists propose quick and pain-free method for diagnosing kidney cancer
January 21, 2019 - Signs of memory loss could point to hearing issues
January 21, 2019 - HeartFlow Analysis shows highest diagnostic performance for detecting coronary artery disease
January 21, 2019 - How Much Caffeine is Too Much?
January 21, 2019 - Take a timeout before you force your child to apologize
January 21, 2019 - Scientists design two AI algorithms to improve early detection of cognitive impairment
January 21, 2019 - Novel therapy for children with chronic hormone deficiency provides lifeline for parents
January 21, 2019 - Bioethicists call for oversight of poorly regulated, consumer-grade neurotechnology products
January 21, 2019 - Study shows hereditary hemochromatosis behind many cancers and joint diseases
January 21, 2019 - Short bouts of stairclimbing throughout the day can improve cardiovascular health
January 20, 2019 - Liver Transplant Survival May Improve With Race Matching
January 20, 2019 - Study implicates hyperactive immune system in aging brain disorders
January 20, 2019 - Cancer Diagnosis May Quadruple Suicide Risk
January 20, 2019 - Parkinson’s disease experts devise a roadmap
January 20, 2019 - Research brings new hope to treating degenerative brain diseases
January 20, 2019 - Scientists pinpoint a set of molecules that wire the body weight center of the brain
January 20, 2019 - Researchers get close to developing elusive blood test for Alzheimer’s disease
January 20, 2019 - UCLA researchers demonstrate new technique to develop cancer-fighting T cells
January 20, 2019 - Researchers discover how cancer cells avoid genetic meltdown
January 20, 2019 - Exercise makes even the ‘still overweight’ healthier: study
January 20, 2019 - University of Utah to establish first-of-its-kind dark sky studies minor in the US
January 20, 2019 - School-based nutritional programs reduce student obesity
January 20, 2019 - Improved maternity care practices in the southern U.S. reduce racial inequities in breastfeeding
January 20, 2019 - New enzyme biomarker test indicates diseases and bacterial contamination
January 20, 2019 - Republican and Democratic governors have different visions to transform health care, say researchers
January 20, 2019 - Researchers discover that spin flips happen in only half a picosecond in the course of a chemical reaction
January 20, 2019 - Suicide Risk Up More Than Fourfold for Cancer Patients
January 20, 2019 - Doctors find 122 nails in Ethiopian’s stomach
January 20, 2019 - UV disinfection technology eliminates up to 97.7% of pathogens in operating rooms
January 20, 2019 - Researchers discover mechanism which drives leukemia cell growth
January 20, 2019 - AHA: Infection as a Baby Led to Heart Valve Surgery for Teen
January 20, 2019 - Injection improves vision in a form of childhood blindness
January 20, 2019 - Multiple sclerosis therapies delay progression of disability
January 20, 2019 - New study finds infrequent helmet use among bike share riders
January 20, 2019 - Clearing up information about corneal dystrophies
January 20, 2019 - Researchers describe new behavior in energy metabolism that refutes existing evidence
January 20, 2019 - New study takes first step toward treating endometriosis
January 20, 2019 - Researchers find how GREB1 gene promotes resistance to prostate cancer treatments
January 20, 2019 - Replacing Sitting Time With Activity Lowers Mortality Risk
January 20, 2019 - A simple, inexpensive intervention makes birth safer for moms and babies in parts of Africa
January 19, 2019 - New anti-inflammatory compound acts as ‘surge protector’ to reduce cancer growth
January 19, 2019 - Significant flaws found in recently released forensic software
January 19, 2019 - New Leash on Life? Staying Slim Keeps Pooches Happy, Healthy
January 19, 2019 - Men and women remember pain differently
January 19, 2019 - Rising air pollution linked with increased ER visits for breathing problems
January 19, 2019 - Study uses local data to model food consumption patterns among Seattle residents
January 19, 2019 - The brain’s cerebellum plays role in controlling reward and social behaviors, study shows
January 19, 2019 - Relationship between nurse work environment and patient safety
January 19, 2019 - Pioneering surgery restores movement to children paralyzed by acute flaccid myelitis
January 19, 2019 - Genetic variants linked with risk tolerance and risky behaviors
January 19, 2019 - New research provides better understanding of our early human ancestors
January 19, 2019 - First-ever tailored reporting guidance to improve patient care and outcomes
January 19, 2019 - 4.6 percent of Massachusetts residents have opioid use disorder
January 19, 2019 - New study suggests vital exhaustion as risk factor for dementia
January 19, 2019 - New antibiotic discovery heralds breakthrough in the fight against drug-resistant bacteria
January 19, 2019 - Ural Federal University scientists synthesize a group of multi-purpose fluorophores
January 19, 2019 - Researchers identify new therapeutic target in the fight against chronic liver diseases
January 19, 2019 - Preparation, characterization of Soyasapogenol B loaded onto functionalized MWCNTs
January 19, 2019 - FDA Approves Ontruzant (trastuzumab-dttb), a Biosimilar to Herceptin
January 19, 2019 - Tobacco use linked with higher use of opioids and sedatives
January 19, 2019 - Study delves deeper into developmental dyslexia
January 19, 2019 - Anti-vaccination movement one of the top health threats in 2019 says WHO
January 19, 2019 - Newly developed risk score more effective at identifying type 1 diabetes
January 19, 2019 - Highly effective protocol to prepare cannabis samples for THC/CBD analysis
January 19, 2019 - Prinston Pharmaceutical Inc. Issues Voluntary Nationwide Recall of Irbesartan and Irbesartan HCTZ Tablets Due to Detection of a Trace Amount of Unexpected Impurity, N-Nitrosodiethylamine (NDEA) in the Products
January 19, 2019 - How does solid stress from brain tumors cause neuronal loss, neurologic dysfunction?
January 19, 2019 - $14.7 million partnership to supercharge vaccine development
January 19, 2019 - Ian Fotheringham receives Charles Tennant Memorial Lecture award
Researchers receive grant to study treatment options for binge eating disorder in veterans

Researchers receive grant to study treatment options for binge eating disorder in veterans

image_pdfDownload PDFimage_print

For the first time, the United States Department of Defense (DOD) has awarded a grant to researchers at University of California San Diego School of Medicine to study binge eating disorder treatments in veterans and active duty military.

“Binge eating and obesity cost the DOD a significant amount of money in health care costs and absenteeism, which impacts the readiness and ability of our men and women who serve,” said Kerri Boutelle, PhD, principal investigator of the study and professor of pediatrics and psychiatry at UC San Diego School of Medicine.

Data suggest that rates of binge eating are high in the military, with approximately 19 percent of women and 14 percent of active duty personnel meeting the criteria for binge eating disorder. In addition, approximately 65 percent of female and 45 percent of male veterans report one or more symptoms of binge eating. The majority of these individuals are overweight or obese, defined by the Centers for Disease Control and Prevention as a measured body mass index of 25 or higher.

Binge eating disorder (BED) is a complex condition that affects the brain and the body. It is characterized by recurrent episodes of consuming large quantities of food, often quickly and to the point of discomfort. BED is the most prevalent of eating disorders and is associated with significant psychiatric and medical comorbidities, including obesity.

“Veterans and active duty service members may be at increased risk for BED due to conditions during military service that encourage eating food quickly with increased stress and pressure and periods of deprivation,” said Boutelle. “Even though there is a high prevalence of binge eating in the military, current treatment options are limited.”

Among the most established treatments for BED is cognitive behavior therapy (CBT), which focuses on changing thoughts and behaviors to reduce harmful acts. CBT results in remission rates of 40 to 60 percent, said Boutelle, but “fails to produce significant weight loss, which results in these individuals continuing to struggle with obesity and the medical and psychological comorbidities.”

With the more than $3 million in funding from the DOD, Boutelle and her collaborators at UC San Diego School of Medicine and Veterans Affairs San Diego Healthcare System will study a novel treatment model called Regulation of Cues (ROC), which targets two underlying mechanisms associated with binge eating and obesity: decreased sensitivity to internal hunger signals and increased sensitivity to external food cues.

ROC trains participants to detect their hunger and fullness to stop eating earlier and to resist tempting foods in the environment through education and learning through experience.

“Our data suggests that ROC can reduce weight and obesity in civilians but has never been compared to CBT for binge eating disorder. While CBT focuses on changing thoughts and avoiding triggering cues to binge, ROC trains participants to tolerate physiological and psychological cravings and to stop eating when full,” said Boutelle. “We believe ROC can potentially provide a more effective and durable treatment for both BED and obesity for veterans. The goal is to help them manage their reaction to food when they are not hungry.”

The clinical trial will enroll 120 veterans with clinical or subclinical diagnoses of BED and obesity. Participants will be randomized to a five-month ROC or CBT program and complete assessments at baseline, mid-treatment, end-of-treatment and six months post-treatment.

“We predict that participants in ROC will decrease their binge eating, nutritional intake and will lose more weight than participants in CBT immediately after treatment and at the six month follow up,” said Boutelle.

With no effective treatments or clinical practice guidelines currently in place for BED in the military, Boutelle says, “this study has the potential to substantially change the treatment model for BED and comorbid obesity. The ROC program is well-developed and could easily be disseminated to veterans and active service personnel through mental health providers.”

Tagged with:

About author

Related Articles