Credit: CC0 Public Domain Do your knees ache? According to new findings from the Oklahoma Medical Research Foundation, your diet could be a culprit. In a study led by OMRF scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice—even when the animals didn’t differ […]Continue Reading ...
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that pregnancies in women with rheumatoid arthritis are associated with premature delivery and low birth weight. Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal […]Continue Reading ...
A study examining how molecules are transported into knee-joint tissue could have major implications for understanding and treating arthritis. UNSW biomedical engineers have shown for the first time that a mixture of variously-sized molecules in the bloodstream can be separated by the constituent tissues of a healthy knee-joint. And an arthritic joint was observed to […]Continue Reading ...
Credit: CC0 Public Domain A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai. The discovery could provide a new pathway for treatment and a way to measure the prognosis of patients diagnosed with the autoimmune condition. Through a […]Continue Reading ...
The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) investigate joint replacement procedures in rheumatoid arthritis (RA) patients. The first study demonstrates that joint replacement procedures have significantly reduced in RA patients in the past decade and the second investigates the impact of biologic therapies on this change […]Continue Reading ...
The results of a study presented at the Annual European Congress of Rheumatology (EULAR 2018) examined rates of malignancy in patients with rheumatoid arthritis (RA), excluding non-melanoma skin cancer (NMSC), and found no difference between those newly treated with tocilizumab (TCZ) versus TNF inhibitors (TNFi). RA is a chronic inflammatory disease that affects a person’s […]Continue Reading ...
Drugs used to treat rheumatoid arthritis may impact mental health by improving pain and stiffness and by targeting inflammatory processes common to arthritis and depression; however, a recent review of published studies demonstrates that relying on rheumatoid arthritis therapies alone may not meaningfully improve patients’ mental health. The findings, which are published in Arthritis & […]Continue Reading ...
Patients with an autoimmune disorder called antineutrophil cytoplasmic antibody-associated vasculitis produce antibodies that damage blood vessels in the body. In some cases, patients’ antibodies target a protein called myeloperoxidase. New research published in Arthritis & Rheumatology indicates that for patients in remission, reappearance of antibodies against myeloperoxidase is a sign that patients will experience a […]Continue Reading ...
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate significant improvements in adherence and clinical outcomes in gout patients who received a daily text message to remind them to take allopurinol. Gout is a very common condition. It is caused by deposits of crystals of a substance […]Continue Reading ...
The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate exciting advances for individuals suffering from systemic lupus erythematosus (SLE). The first is a phase II clinical study of a promising oral treatment, baricitinib. The second demonstrates the effective use of the shingles vaccine in SLE patients who […]Continue Reading ...
The results of a population study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate a significantly increased rate of self-harm attempts in inflammatory arthritis (IA), particularly following a diagnosis of Ankylosing Spondylitis (AS). Results of the study showed that individuals with AS were almost twice as likely to self-harm as their […]Continue Reading ...
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) suggest that over two thirds of the increased cardiovascular risk associated with osteoarthritis is linked to the use of non-steroidal anti-inflammatory drugs (NSAIDs). Osteoarthritis is a common condition that makes a person’s joints stiff and painful, particularly in the […]Continue Reading ...
To diagnose rheumatoid arthritis, antibodies to the amino acid citrulline are commonly measured. A new study from Uppsala University shows that a broad mix of different antibodies in the joints is the dominant factor that can be associated with severe inflammation and joint damage. These findings, published in Annals of the Rheumatic Diseases, may eventually […]Continue Reading ...
Credit: University of Michigan In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain. A new study published in Nature Communications examines this issue. “Rheumatoid arthritis is an inflammatory and autoimmune condition with nasty levels of inflammation that can affect a person’s joints […]Continue Reading ...
Joint space in hip, knee and ankle joints as analyzed by the JSM algorithm. Credit: Tom Turmezei An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University […]Continue Reading ...
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