Coronal section of human brain indicating the lateral temporal lobe (red circle) used in this study. Credit: Coronal section of human brain indicating The lab of Shelley Berger, PhD, Perelman School of Medicine, University of Pennsylvania Although certain genetic variants increase the risk of Alzheimer’s disease (AD), age is the strongest known risk factor. But […]Continue Reading ...
William Kremen, PhD, professor of psychiatry at UC San Diego School of Medicine. Credit: UC San Diego Health For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify […]Continue Reading ...
March 6, 2018 Although certain genetic variants increase the risk of Alzheimer’s disease (AD), age is the strongest known risk factor. But the way in which molecular processes of aging predispose people to AD, or become impaired in AD remains a mystery. A team of researchers from the Perelman School of Medicine at the University […]Continue Reading ...
In the operating room Brown monitors patient EEG readings in real time to adjust anesthetic dosing. Often he can safely and comfortably give less than the supposedly needed dose. Credit: Len Rubinstein/MIT It’s intuitive that anesthesia operates in the brain, but the standard protocol among anesthesiologists when monitoring and dosing patients during surgery is to […]Continue Reading ...
Researchers hope that their work will lead to a new approach to designing and evaluating polymer stents and other types of degradable medical devices. Credit: Pei-Jiang Wang Many patients with heart disease have a metal stent implanted to keep their coronary artery open and prevent blood clotting that can lead to heart attacks. One drawback […]Continue Reading ...
After extensive research, investigators at Hospital for Special Surgery (HSS) have developed the first-ever patient questionnaire to measure the physical and emotional impact of brachial plexus injury (BPI). The survey also seeks to assess patients’ expectations and treatment outcomes. The research and the copyrighted questionnaire were published in the Journal of Bone & Joint Surgery […]Continue Reading ...
Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.Continue Reading ...
Resolving Interfacial Protein Dynamics by STReM Prof. Christy Landes STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.Continue Reading ...
Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. SAN DIEGO — Patients with moderate or severe atopic dermatitis (AD) had as much as 74% improvement in disease status with the oral […]Continue Reading ...
March 5, 2018 For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered […]Continue Reading ...
HIV infecting a human cell. Credit: NIH Drawing from data collected for years by AIDS researchers in six African nations, scientists have pinpointed seven bacterial species whose presence in high concentrations may significantly increase the risk of HIV infection in women. The findings add strength and precision to a growing body of evidence that the […]Continue Reading ...
Action Points Be aware that cardiac MRI stress T1 mapping accurately detected and differentiated between obstructive epicardial coronary artery disease (CAD) and microvascular dysfunction, without contrast agents or radiation, and was superior to gadolinium-based first-pass perfusion imaging for detecting obstructive epicardial CAD. Be aware, also, that in angina patients with non-obstructive coronary artery disease, cardiac […]Continue Reading ...
Credit: CC0 Public Domain Say you’re the coach of a basketball team that’s trailing by two points in the dying seconds of a game. Your team has the ball and you call a timeout to set up a play. Or imagine your football team has just scored a touchdown with three seconds to play to […]Continue Reading ...
Credit: CC0 Public Domain Losing weight is, for most people, the easy part. The bigger challenge is trying to keep it off for more than a year. New research helps explain why people in this second stage are so much more prone to failure. In a nutshell, people who have shed a significant chunk of […]Continue Reading ...
Credit: University of Michigan When a patient breaks a bone, there’s a possibility the fracture won’t heal properly or quickly—even with the aid of pins, plates or a cast. And use of another restorative tactic known as bone morphogenetic proteins, or BMPs, is increasingly less likely. Designed to promote spinal fusion and bone repair more […]Continue Reading ...
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