One in five people with Alzheimer’s disease (AD) who use a benzodiazepine are also concomitant users of an opioid, according to a new study from the University of Eastern Finland. Concomitant use was more common in comparison persons, but those with AD used strong opioids more frequently. About half of all concomitant users were prolonged […]Continue Reading ...
Alzheimer’s disease (AD) is a progressive, neurodegenerative condition in which individuals exhibit memory loss, dementia, and impaired metabolism. Nearly all previous single-domain studies to treat AD have failed, likely because it is a complex disease with multiple underlying drivers contributing to risk, onset, and progression. Keine et al. explored the efficacy of a multidomain therapy […]Continue Reading ...
Brain scans are one method used to measure the amount of amyloid in the brain, which may be a sign of mild cognitive impairment. Credit: The University of Miami Miller School of Medicine Finding an effective way to identify people with mild cognitive impairment who are most likely to go on to develop Alzheimer’s disease […]Continue Reading ...
Alzheimer’s disease (AD) is a brain disease that causes changes that kill brain cells. AD is a type of dementia, which causes memory loss and problems with thinking and making decisions. People with AD and other forms of dementia have difficulties performing the daily activities others might consider routine. Dementia takes a toll on those […]Continue Reading ...
Researchers have succeeded in training an artificial intelligence (AI) algorithm to predict the risk of cognitive decline which could result in Alzheimer’s disease (AD) five years later. Image Credit: Atthapon Raksthapu / Shutterstock At present, there is no effective treatment or cure for AD, but a growing volume of evidence suggests that the disease […]Continue Reading ...
The National Institute on Aging (NIA) has awarded scientists at University of California San Diego School of Medicine and San Diego State University (SDSU) with a five-year, $4 million grant to boost the number of Latino and other underrepresented minority researchers studying Alzheimer’s disease (AD) and related dementias afflicting seniors of Latino origins, a demographic […]Continue Reading ...
Finding an effective way to identify people with mild cognitive impairment who are most likely to go on to develop Alzheimer’s disease has eluded researchers for years. But now, a team of researchers led by David Loewenstein, Ph.D., director of the Center for Cognitive Neuroscience and Aging (CNSA) and professor of psychiatry and behavioral sciences […]Continue Reading ...
By Liji Thomas, MDAugust 17, 2018 An intriguing new study has marked the beginning of the answer to a medical mystery: why is it that some people with classic markers for Alzheimer’s Disease never show any signs of dementia throughout their life? Image Credit: SpeedKingz / Shutterstock Alzheimer’s disease (AD) is the most widespread form […]Continue Reading ...
Old age is the greatest risk factor for many diseases, including Alzheimer’s disease (AD) and cancer. Geroprotectors are a recently identified class of anti-aging compounds. New Salk research has now identified a unique subclass of these compounds, dubbed geroneuroprotectors (GNPs), which are AD drug candidates and slow the aging process in mice. “The argument for […]Continue Reading ...
Home News Professional Abnormalities in Genes Linked to IRSP in Alzheimer’s Disease MONDAY, Nov. 5, 2018 — Individuals with Alzheimer’s disease (AD) have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway (IRSP), according to a study published online Nov. 1 in PLOS […]Continue Reading ...
Alzheimer’s disease (AD) is the most common form of dementia, involving memory loss and a reduction in cognitive abilities. Patients with AD develop multiple abnormal protein structures in their brains that are thought to destroy or damage nerve cells (neurons). One of these structures, the senile plaque, is made up of clumps of beta-amyloid (Aβ) […]Continue Reading ...
PET scan of a human brain with Alzheimer’s disease. Credit: public domain Researchers from Boston University School of Medicine, working with scientists across the nation on the Alzheimer’s Disease Sequencing Project (ADSP), have discovered new genes that will further current understanding of the genetic risk factors that predispose people to the development of Alzheimer’s disease […]Continue Reading ...
Sep 24 2018 Cytox, a precision medicine company which today is commercializing polygenic risk scoring (PRS) approaches for assessing genetic risk for developing Alzheimer’s disease (AD) and other neurological diseases, has announced it has expanded its research collaboration with the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL) to test new algorithms for […]Continue Reading ...
Screen shot of Jackson Laboratory-Alzheimer’s Association slide: Together we can end Alzheimer’s disease. Credit: The Jackson Laboratory The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer’s disease (AD), has released eight new models carrying genetic mutations found in patients. In past decades, most AD researchers had to rely […]Continue Reading ...
August 1, 2018 A new method published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging constructs networks based on multiple structural features to identify Alzheimer’s disease and mild cognitive impairment Researchers have developed a new method for constructing personal brain networks using multiple structural features to improve the accuracy of diagnosing Alzheimer’s disease (AD) and mild […]Continue Reading ...
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