Emergency room doctors often have only a few minutes to determine which patients are in need of a blood transfusion. But currently doctors have no direct method to assess the health of one of the most critical component of the blood: platelets. These tiny blood cells play a huge role in helping blood clot after […]
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A new reversible, drug-free antiplatelet therapy could reduce the risk of blood clots and potentially prevent cancer metastasis, according to a study published today in Science Translational Medicine. The therapeutic approach involves modifying human platelets to create “decoys” that are still capable of binding to some cells but will not aggregate or carry out the […]
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Researchers have developed a way to grow human platelets in the laboratory from stem cells derived from fat tissue. The achievement, reported today in the journal Blood, suggests manufactured platelets could eventually reduce the reliance on donated platelets to help patients with cancer and other disorders. Platelets are a component of blood that helps with […]
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Premature babies with low levels of platelets (thrombocytes) in their blood run a greatly increased risk of being afflicted with a severe variation of retinopathy of prematurity (ROP), an eye disease that can cause blindness, according to a study from Sweden and US published in the journal JCI Insight. In experiments on mice, injections of […]
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June 25, 2018 Platelets are uniquely mammalian cells, and are the small cells of the blood that are critical for us to stop bleeding when we cut ourselves. They are also a central part of the process of thrombosis, which underlies heart attacks and stroke, and form the target of major drugs used in the […]
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This diagram illustrates how UBC scientists modified platelets, and how that modification affects coagulation. Credit: Vivienne Chan and Christian Kastrup, University of British Columbia Blood platelets have one main job: Stop bleeding by forming clots. Sometimes, however, these tiny cell fragments fail when they are needed most – when a person is experiencing massive bleeding, […]
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Stylized representation of a platelet and T mobile. Plus and unfavourable indicators are used to symbolically point out the certain (clotting) and unfavourable (downregulating T mobile immunity) results of platelets. Credit score: Emma Vought of the Clinical College of South Carolina. Blood platelets assist conceal most cancers from the immune device by means of suppressing […]
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An unexpected finding in pre-clinical platelet studies by Baker Institute researchers could provide a novel approach to targeting and destroying difficult-to-treat cancer cells, providing new therapeutic options for a range of cancers. This latest finding, published in the journal Theranostics, was discovered while studying activated platelets in the setting of heart disease and may now […]
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Screening for ROP at Sahlgrenska University Hospital. Credit: Ann-Sofie Petersson Premature babies with low levels of platelets (thrombocytes) in their blood run a greatly increased risk of being afflicted with a severe variation of retinopathy of prematurity (ROP), an eye disease that can cause blindness, according to a study from Sweden and US published in […]
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Credit: CC0 Public Domain For patients diagnosed with a Staphylococcus aureus infection, often referred to as a staph or MRSA infection, every minute counts. The bacteria create havoc in the body. The immune system goes into overdrive. The heightened immune response can lead to sepsis, which kills 30 to 50 per cent of the people […]
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May 16, 2018 The most severe allergic reaction, anaphylaxis (or anaphylactic shock), is the result of an inappropriate immune reaction following the introduction of a usually harmless antigen into the body. The production of antibodies against this antigen (or allergen) allows the formation of antibody-antigen complexes that trigger a massive secretion of potent mediators, resulting […]
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August four, 2017 Platelets, the cells in blood that permit clotting, are extremely reliant on their talent to metabolize glucose, in step with a brand new learn by way of researchers on the College of Iowa. The findings, revealed in Mobile Studies and in a similar paper revealed in Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB), […]
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