Feb 19 2019 By studying fish raised in aquaculture, researchers from the Helmholtz Zentrum München, the University of Copenhagen and the University of Campinas in Brazil have shed new light on the mechanisms by which antibiotic resistance genes are transferred between bacteria. According to the study published in the journal ‘Microbiome’, those mechanisms are more […]Continue Reading ...
The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract. However, it can also cause life-threatening infections, especially in immunocompromised patients. These infections are usually treated with the drug fluconazole, which inhibits the synthesis of ergosterol in Candida. Ergosterol fulfils similar important functions in fungi as cholesterol in […]Continue Reading ...
When President Donald Trump demands a border wall or threatens to deport young unauthorized immigrants, one of the loudest opposition voices comes from the son of Mexican immigrants — who also happens to be California’s top lawyer. Democrat Xavier Becerra, the state’s first Latino attorney general, is not only one of Trump’s biggest critics, he […]Continue Reading ...
Study identifies key step in spread of drug resistance, opportunity for intervention Spotless surfaces in hospitals can hide bacteria that rarely cause problems for healthy people but pose a serious threat to people with weakened immune systems. Acinetobacter baumannii causes life-threatening lung and bloodstream infections in hospitalized people. Such infections are among the most difficult […]Continue Reading ...
Increased levels of antibiotic resistant bacteria in the environment may have different causes. It could be a consequence of on-site selection from antibiotic residues in the environment, hence promoting the evolution of new forms of resistance. Alternatively, it is simply due contamination by fecal bacteria that often tend to be more resistant than other bacteria. […]Continue Reading ...
Researchers at Osaka University have discovered that polymyxin E-resistant Escherichia coli is widely prevalent among people living in rural Vietnam. Kateryna Kon | Shutterstock Polymyxin E is an antibiotic that is used to prevent the growth of Gram-negative bacteria such as E.coli and Pseudomonas aeruginosa. It is one of only a few remaining drugs that […]Continue Reading ...
Researchers at the University of Pennsylvania have found that two mechanisms used by a subset of melanoma to resist treatment are connected to each other. The finding could pave the way for new approaches to overcome resistance to therapies. Crevis | Shutterstock Scientists were already aware of the two resistance mechanisms, but until now, the […]Continue Reading ...
Researchers at LSTM have used a bioinformatics approach to integrate information from multiple studies on insecticide resistance in mosquitoes and uncovered a number of important resistance mechanisms that had not previously been recognized. In a study published in Nature Communications, Dr Victoria Ingham and colleagues have utilized specialist computer programming to better understand the mechanisms […]Continue Reading ...
Feb 13 2019 The new Deeplex®-MycTB mycobacterial antibiotic resistance test, developed by GenoScreen, has been used by an international research team in a molecular epidemiology study published in The Lancet Infectious Diseases. This study highlights the spread of tuberculosis strains resistant to first-line antibiotics, not detected by actual international tests. 1: Visualisation and interpretation of […]Continue Reading ...
The UK government has launched a 5-year action plan outlining how the nation intends to contribute to the containment and control of antimicrobial resistance by the year 2040. Kateryna Kon | Shutterstock The government’s goals include a 10% reduction in the number of drug-resistant infections by 2025 and the prevention of at least 15,000 new […]Continue Reading ...
The Staphylococcus aureus bacterium is one of the commonest pathogens and can even cause sepsis. The new antibiotic dalbavancin is very effective against many bacterial pathogens. However, resistance to the antibiotic was seen to develop during the long-term treatment of a patient with an infection caused by an implanted cardiac device. A team of researchers […]Continue Reading ...
Crystal structure of a portion of the HER2 protein. Credit: RCSB PDB Metastatic breast cancers treated with hormone therapy can become treatment-resistant when they acquire mutations in the human epidermal growth factor receptor 2 (HER2) that were not present in the original tumor, reports a team led by scientists from Dana-Farber Cancer Institute and the […]Continue Reading ...
A model of ER Translocation Credit: Penn Medicine Drugs that target BRAF and MEK in cancer have shown promise in treating a subset of melanoma that carries a mutation in the BRAF gene, but drug resistance usually emerges, reversing the benefit of these drugs and limiting the survival of patients. Research has shown tumors have […]Continue Reading ...
Researchers found that widespread, low-intensity use of antibiotics may play more of a role in antibiotic resistance than high-intensity, repeated use by a small fraction of the population The increasing prevalence of antibiotic resistance in the U.S. appears more closely linked with their occasional use by many people than by their repeated use among smaller […]Continue Reading ...
Researchers at the University of Nebraska-Lincoln have found evidence that the epigenetics-based evolution that occurs in complex multicellular species (eukaryotes) is also at play in a species of archaea, which are microscopic, single-celled organisms. Kateryna Kon | Shutterstock The discovery could improve scientists’ ability to explore and answer questions about epigenetic processes in humans. Through […]Continue Reading ...
- Study sheds new light on how antibiotic resistance genes are transferred between bacteria
- Chronic Wasting Disease may soon spread to humans, warns CDC
- Scientists identify new genetic causes linked to abnormal pregnancies and miscarriages
- Using LyoSpeed technology to avoid residual solvent when drying HPLC fractions
- New screening tool more likely to identify sexual and labor exploitation of youth
- Newly licensed nurses work for long hours, also have a second paid job
- Physicists identify simple mechanism used by deadly bacteria to fend off antibiotics
- FDA Grants Priority Review to Genentech’s Personalized Medicine Entrectinib
- Exposure to chemicals before and after birth is associated with a decrease in lung function
- Neuroscientists reveal that simple brain region can guide complex feats of mental activity
- Study finds new link between food allergies and multiple sclerosis
- First gene therapy operation for macular degeneration is a success
- Physicians graduated outside the U.S. offer better care for Medicare patients with complex needs
- FDA Approves Keytruda (pembrolizumab) for the Adjuvant Treatment of Patients with Melanoma with Involvement of Lymph Node(s) Following Complete Resection
- Study identifies brain cells that modulate behavioral response to threats
- Researchers take closer look at how viruses bind cells and cause infection
- Newly developed gene therapy helps decelerate aging process
- Study suggests new treatment strategy for deadly brain cancer
- Scientists develop unique hybrid implant that imitates bone structure
- Push-ups can be tailored to meet specific needs of individuals