Research published today shows that circulating tumor cell count may provide an effective indicator of appropriate treatment choice for metastatic breast cancer. The risk of death was 35% lower among patients whose treatment was escalated according to the level of circulating tumor cells. Suzi44 | Shutterstock It has been estimated that more than 154,000 women […]Continue Reading ...
The spread of invasive cancer cells from a tumor’s original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience, University of California San Diego School of Medicine researchers reported engineering sensors that can detect and […]Continue Reading ...
As tumors develop, they evolve genetically. How does the immune system act when faced with tumor cells? How does it exert pressure on the genetic diversity of cancer cells? Scientists from the Institut Pasteur and Inserm used in vivo video techniques and cell-specific staining to visualize the action of immune cells in response to the […]Continue Reading ...
A new study has revealed that breast cancer cells recruit bone marrow-derived fibroblasts to enhance their growth. It is hoped that the discovery will lead to the development of new treatments that target the cells in and around the tumor. DrimaFilm | Shutterstock Many breast cancers show the presence of abundant fibroblasts from neighboring breast […]Continue Reading ...
WHIPPANY, N.J., Oct. 21, 2018 /PRNewswire/ — Bayer and Loxo Oncology, Inc. (Nasdaq: LOXO), today announced updated clinical data for larotrectinib in adult and pediatric patients with TRK fusion cancer across 24 unique tumor types. The update included approximately one year of additional follow-up for a primary dataset of 55 patients as well as results […]Continue Reading ...
Instead of destroying a tumors’ blood supply, a first-ever University of Guelph study has proven that opening up the vessels is potentially more effective when it comes to fighting ovarian cancer. This is because open vessels provide a clear pathway for treatment to attack the tumor. “There hasn’t been much hope for women with ovarian […]Continue Reading ...
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a method by which fibroblasts surrounding pancreatic cancer cells can be reprogrammed to suppress, rather than promote, tumor cell growth. Image Credit: CSHL, 2018 The research was published today in the journal Cancer Discovery, and details a signaling pathway in pancreatic tumors that could help them […]Continue Reading ...
Researchers at La Jolla Institute for Immunology (LJI) and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute’s Cancer Moonshot initiative. The funding will support research to develop new and improved immunotherapeutic treatment options for patients with head and neck cancer. Led by LJI Professor Stephen Schoenberger, Ph.D., […]Continue Reading ...
Russian researchers announced the development of a combined action drug based on ionizing radiation and bacterial toxin. Their total effect appeared to be 2,200 times stronger compared to that exerted by the radiation and toxin, separately. The drug affects tumor cells selectively providing better diagnostics and treatment of malignant tumors. These advances were reported in […]Continue Reading ...
Researchers at the Johns Hopkins Kimmel Cancer Center say they have added to evidence that measuring and monitoring tumor DNA that naturally circulates in the blood of melanoma patients can not only reliably help reveal the early stages of cancer growth and spread but also uncover new treatment options that tumor genetic analysis alone may […]Continue Reading ...
What are lung cancer tumor marker tests? Lung cancer tumor markers are substances produced by tumor cells. Normal cells can turn into tumor cells due to a genetic mutation, a change in the normal function of genes. Genes are the basic units of heredity passed down from your mother and father. Some genetic mutations can […]Continue Reading ...
Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine. Liquid biopsies are fluid samples from patients, for example from the blood or urine, which provide a less invasive way to monitor disease compared to tumor biopsies. A less intrusive test […]Continue Reading ...
Nanosystems that deliver anticancer drugs or imaging materials to tumors are showing significant progress, particularly those that respond to tumor-related stimuli, according to a review published in the journal Science and Technology of Advanced Materials. However, further research is still required to make sure these delivery systems are stable, non-toxic and biodegradable. Nanocarriers designed to […]Continue Reading ...
Oct 19 2018 An interview with Dr. Andrew Ewald, Ph.D., discussing the influence of the myoepithelium on breast cancer growth and the importance of studying metastasis. What is the tumor microenvironment and how is it linked to metastasis? The tumor microenvironment is a general term describing all the things that are a part of the […]Continue Reading ...
A new blood test for children with brain tumors offers a safer approach than surgical biopsies and may allow doctors to measure the effectiveness of treatment even before changes are identified on scans, according to research led by UCSF Benioff Children’s Hospitals and Children’s National Health System. Unlike a standard brain biopsy, which entails drilling […]Continue Reading ...
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