Breaking News
April 20, 2018 - Pelizaeus-Merzbacher-like disease type 1 – Genetics Home Reference
April 20, 2018 - Tick-borne diseases reach epidemic levels, panel says
April 20, 2018 - A potential “male pill” without side effects
April 20, 2018 - Researchers discover new information related to rare form of leukemia
April 20, 2018 - Researchers find crucial links between dopamine and avoidance behavior
April 20, 2018 - UGA scientist creates system for efficient detection of foodborne pathogens
April 20, 2018 - Social Support of Autonomy Tied to Better Glycemic Control in DM
April 20, 2018 - Study reports use of nutritional ketosis with mobile app intervention could reverse Type 2 diabetes
April 20, 2018 - New microscopy techniques allow quasi-biochemical studies on living T cells
April 20, 2018 - Study shows connection between muscular strength and brain health
April 20, 2018 - Ecolab introduces Life Sciences cleanroom program in North America
April 20, 2018 - Male fruit flies like sex and alcohol
April 20, 2018 - Improving job prospects unlikely to control opioid epidemic
April 20, 2018 - Skin Sensor Might Someday Track Alcoholics’ Booze Intake
April 20, 2018 - The relevance of GABA for diabetes highlighted in two new studies
April 20, 2018 - Novel method enables fast and noninvasive assessment of tumor status
April 20, 2018 - IU psychologist receives NIH grant to study earliest phases of language learning in children
April 20, 2018 - Walking fast lowers risk of hospitalization in heart patients, shows study
April 20, 2018 - Young victims of cyberbullying twice as likely to attempt suicide and enact suicidal behavior
April 20, 2018 - Role of UBE3A enzyme in Angelman syndrome
April 20, 2018 - NovaDigm Therapeutics initiates NDV-3A Phase 2a study for reduction of S. aureus in military trainees
April 20, 2018 - High-tech microscope reveals how cancer-causing virus anchors itself to human DNA
April 20, 2018 - Experimental compound reduces destructive inflammation to improve stroke outcome
April 20, 2018 - The May issue of Drug Discovery Today is a Special Issue and will be published very soon
April 20, 2018 - Larger families linked to heightened tooth loss risk for moms
April 20, 2018 - Scientists develop tiny fluorescent probe that seeks out GLUT5 and detects cancer cells
April 20, 2018 - The Swedish Childhood Cancer Foundation awards grant to KI researchers
April 20, 2018 - AMSBIO’s MC-Easy minicircle technology allows sustained transgene expression in quiescent cells and tissues
April 20, 2018 - Researchers use optogenetics to treat chronic pain
April 20, 2018 - Discovery of 100 new genes may aid research into pigmentation
April 20, 2018 - AYOXXA introduces new LUNARIS Mouse 12-Plex Th17 Kit for quantitative analysis of Th17 cell biology
April 20, 2018 - Compound derived from immune cells treats psoriasis in mice
April 20, 2018 - GABA-transaminase deficiency – Genetics Home Reference
April 20, 2018 - Key heart risks decline for older Americans
April 20, 2018 - UD professor wins $2.3 million grant from NIH for research on Achilles tendinopathy
April 20, 2018 - Researchers discover unique protein in malaria parasite that could be new drug target
April 20, 2018 - Bio-Techne expands automation capabilities of popular RNAscope ISH technology
April 20, 2018 - Smartphone app effective in promoting proper child car seat practices
April 20, 2018 - Nutraceuticals could play an important role in preventing heart disease
April 20, 2018 - FDA Alert: Certain Kratom-Containing Powder Products by Viable Solutions: Recall -Possible Salmonella Contamination
April 20, 2018 - What is heart failure?
April 20, 2018 - TIP Biosystems introduces handheld UV-Visible spectrophotometer for photometric measurements
April 20, 2018 - Inactivity of astronauts during spaceflights may have more pronounced effect on skeletal muscle than hypoxia
April 20, 2018 - New SIDS Info app seeks to reduce infant sleep-related deaths
April 20, 2018 - Wide-scale distribution of naloxone effectively prevents overdose deaths, study finds
April 20, 2018 - Triple-negative breast cancer found to be chemoresistant prior to treatment
April 20, 2018 - ACL tears occur the same way in women and men, study finds
April 20, 2018 - UT Southwestern researchers identify 170 potential therapeutic targets for lung cancer
April 20, 2018 - Finding the ‘keyhole’ to beat obesity at the cellular level
April 20, 2018 - Long-term exposure to cold temperatures reduces diabetes and obesity, shows study
April 20, 2018 - Metabolic Syndrome Common With Chronic Hep B Infection
April 20, 2018 - Tracking quality of life during prostate cancer treatment
April 20, 2018 - Study shows presence of beta-amyloid dimers in the brains of Alzheimer’s patients
April 20, 2018 - Researchers identify link between physical inactivity and increased risk of dying from cancer
April 20, 2018 - Breathtaking evolution amongst Indonesian tribe
April 20, 2018 - Study shows testosterone deficiency in men is associated with chronic diseases
April 20, 2018 - Simple one-page form helps improve satisfaction of patients with care
April 20, 2018 - Researchers evaluate accuracy of simple blood test to predict lung cancer
April 20, 2018 - Study looks at sperm producing ability in testicular cancer patients
April 20, 2018 - Exercise In, Vitamin D Out for Preventing Falls: U.S. Panel
April 20, 2018 - Skin cancers associated with decreased risk of developing AD
April 20, 2018 - Preserving fertility during chemotherapy
April 20, 2018 - Teva and Procter & Gamble Company terminate PGT Healthcare partnership
April 20, 2018 - People diagnosed with traumatic brain injury may have increased risk of Parkinson’s disease, shows study
April 20, 2018 - Researchers use smartphone to diagnose people infected with Loa loa worm
April 20, 2018 - College students with autism have high rate of suicidal thoughts
April 20, 2018 - Study sheds light on how the HSC niche is maintained
April 20, 2018 - Drug test spurs frank talk between hypertension patients and doctors
April 19, 2018 - Low-cost deworming drug improves female farmers’ physical fitness
April 19, 2018 - Genome editing identifies neural circuit behind leptin’s anti-obesity and anti-diabetes effects
April 19, 2018 - Many European countries lack comprehensive policy to eliminate viral hepatitis
April 19, 2018 - Young people with ADHD ‘more likely’ to come from deprived neighbourhoods
April 19, 2018 - SLU professor discovers new biomarkers for chlorine gas exposure
April 19, 2018 - Study proposes new mechanism that may contribute to gender differences in weight control
April 19, 2018 - Sleep restriction therapy does not interfere with insomnia patient’s driving ability, research shows
April 19, 2018 - Deep brain stimulation offers relief to UTHealth patient with treatment-resistant depression
April 19, 2018 - Study shows fatty fish and camelina oil boost HDL and IDL cholesterol
April 19, 2018 - FDA Alert: Euphoric Capsules by Epic Products: Recall
April 19, 2018 - Researchers identify peptide produced during cartilage deterioration as a potential source of osteoarthritis pain
April 19, 2018 - New breakthrough may allow scientists to orchestrate tissue regeneration in humans

U.S. Strikes to Avert Scarcity of Yellow Fever Vaccine

image_pdfDownload PDFimage_print

FRIDAY, April 28, 2017 — As a brand new outbreak of mosquito-borne yellow fever continues to develop in Brazil, U.S. well being officers say they are taking steps to avert any scarcity of vaccine vacationers may want.

On Friday, the U.S. Facilities for Illness Regulate and Prevention defined plans to “make certain a continuing yellow fever vaccine provide in the US,” as a result of present stockpiles are anticipated to be depleted through mid-2017.

The CDC identified that during 2016, Sanofi Pasteur, the maker of the YF-VAX shot towards yellow fever, was once pressured to curb manufacturing of the vaccine because of “a producing factor.”

“No yellow fever vaccine is anticipated to be to be had through mid-2017,” the CDC mentioned in a information unlock. “YF-VAX is the one yellow fever vaccine authorized to be used in the US and is shipped to roughly four,000 health center websites.”

On the other hand, a 2d yellow fever vaccine, known as Stamaril, will probably be made to be had at 250 clinics national, the CDC mentioned. Stamaril is manufactured in France through Sanofi Pasteur.

“As a result of yellow fever is a doubtlessly severe illness, CDC and Sanofi Pasteur collaborated on a plan to distribute restricted amounts of Stamaril yellow fever vaccine to forestall other people from changing into inflamed through the virus till manufacturing of YF-VAX resumes at a brand new facility in 2018,” the company defined.

U.S. well being officers have just lately sounded the alarm over yellow fever.

In an essay printed April 13 within the New England Magazine of Drugs, Dr. Anthony Fauci, director of the U.S. Nationwide Institute of Hypersensitivity and Infectious Illnesses, and colleague Dr. Catharine Paules mentioned that an enormous outbreak of yellow fever in Brazil should be intently monitored.

Yellow fever has a fairly prime demise charge and “is essentially the most critical [insect-transmitted] virus ever to flow into within the Americas,” Fauci and Paules wrote.

“Despite the fact that it’s extremely not likely that we will be able to see yellow fever outbreaks within the continental United States . . . it’s conceivable that travel-related instances of yellow fever may happen, with temporary classes of native transmission in hotter areas such because the Gulf Coast states, the place A. aegypti mosquitoes are prevalent,” the workforce added.

In keeping with the infectious illness mavens, yellow fever has the possible to be the 5th mosquito-borne an infection to seem within the continental United States because the 1990s, following dengue, West Nile, chikungunya and the Zika virus.

Yellow fever is possibly essentially the most bad of the ones 5, on the other hand. In a single outbreak that started within the Congo in December 2015, there have been 137 deaths amongst 961 showed instances, the file famous.

And within the present Brazilian outbreak, there have to this point been loads of instances and dozens of showed deaths, in step with well being government.

Extra ominous within the Brazilian outbreak is the truth that the sickness seems to be shifting from its conventional rural atmosphere in opposition to the towns.

“The outbreak is affecting spaces in shut proximity to primary city facilities [in Brazil] the place yellow fever vaccine isn’t robotically administered,” Fauci and Paules warned.

The authors stressed out that there is no proof but that mosquitoes are transmitting yellow fever between inflamed other people. On the other hand, the arrival of outbreaks close to city facilities “raises worry that, for the primary time in many years, city transmission of yellow fever will happen in Brazil,” they defined.

The illness isn’t a whole stranger to the US, even if scientists say the final primary outbreak lies a long way again in historical past.

“The Philadelphia yellow fever epidemic of 1793, as an example, killed roughly 10 % of the town’s inhabitants,” Fauci and Paules famous.

Fortuitously for American citizens nowadays, the yellow fever vaccine — first evolved in 1937 — is efficacious in combating sickness. The present vaccine is considered 99-percent efficient over an entire life.

For the ones already inflamed, it is an important that signs are noticed early.

On the other hand, “early popularity could also be tough in international locations similar to the US, the place maximum physicians have by no means noticed a case of yellow fever,” the authors identified. Early signs come with a fever that may mimic flu, adopted through a duration of remission, after which a level known as “intoxication” — prime fever, liver disorder and jaundice, or even kidney failure, center and frightened device disorder, and surprise.

No such instances have emerged in the US, however world journey approach unvaccinated other people may carry the sickness again house after visiting a deadly disease space.

The yellow fever outbreak comes because the Zika virus continues to have an effect on international locations all over the Americas. Each viruses are unfold through the similar mosquito species.

To forestall the Brazil outbreak from spreading, “early identity of instances and fast implementation of public well being control and prevention methods, similar to mosquito keep an eye on and suitable vaccination, are essential,” Fauci and Paules concluded.

Additional information

The U.S. Facilities for Illness Regulate and Prevention has extra on yellow fever.

Posted: April 2017

Really helpful for you

View feedback

Tagged with:

About author

Related Articles