Breaking News
December 14, 2018 - Researchers discover Ebola-fighting protein in human cells
December 14, 2018 - Fentanyl surpasses heroin in cause of U.S. drug overdose deaths
December 14, 2018 - When Heart Attack Strikes, Women Often Hesitate to Call for Help
December 14, 2018 - A warning about costume contacts
December 14, 2018 - Study examines link between peripheral artery disease and heart attack
December 14, 2018 - Researchers develop biotechnological tool to produce antifungal proteins in plants
December 14, 2018 - 3D-printed adaptive aids can benefit patients with arthritis
December 14, 2018 - Chronic bullying during adolescence impacts mental health
December 14, 2018 - Integral Molecular and Merus collaborate to develop bispecific antibody therapeutics
December 13, 2018 - Importance of cell cycle and cellular senescence in the placenta discovered
December 13, 2018 - Gold “nanoprisms” open new window into vessels and single cells
December 13, 2018 - Research findings could lead to new targets for cancer-fighting therapeutics
December 13, 2018 - Butantan Institute signs collaboration agreement with MSD to develop dengue vaccines
December 13, 2018 - Study explores how patients want to discuss symptoms with doctors
December 13, 2018 - RUDN medics first to gather scattered data on hepatitis morbidity in Somalia
December 13, 2018 - Age and gender disparities found in use of bed nets to prevent malaria in sub-Saharan Africa
December 13, 2018 - Caffeine therapy benefits developing brains of premature babies
December 13, 2018 - New review focuses on electrospinning techniques used in musculoskeletal tissue engineering
December 13, 2018 - A new division focused on human immune system
December 13, 2018 - Zogenix Announces Positive Phase 3 Trial Results on the Efficacy and Safety of Fintepla (ZX008) in Dravet Syndrome
December 13, 2018 - BCR ABL Genetic Test: MedlinePlus Lab Test Information
December 13, 2018 - Caffeinated beverages during pregnancy linked to lower birth weight babies
December 13, 2018 - Stanford Medicine Health Trends Report examines opportunity to democratize health care
December 13, 2018 - Obsessive-compulsive disorder may protect individuals from obesity
December 13, 2018 - Scientists investigate how a painful event is processed in the brain
December 13, 2018 - Genetic study reveals new insights into underlying causes of moderate-to-severe asthma
December 13, 2018 - Vitamin C supplementation for pregnant smokers may reduce harm to infants’ lungs
December 13, 2018 - New study reveals yin-yang personality of dopamine
December 13, 2018 - Research identifies nerve-signaling pathway behind sustained pain after injury
December 13, 2018 - Children with high levels of callous traits show widespread differences in brain structure
December 13, 2018 - Long-term Benefit of Steroid Injections for Knee Osteoarthritis Challenged
December 13, 2018 - Adding new channels to the brain remote control
December 13, 2018 - In the Spotlight: A different side of neuroscience
December 13, 2018 - Medical Marvels: Using immunotherapy for melanoma that spread to the brain
December 13, 2018 - Puzzles do not keep dementia away finds study
December 13, 2018 - New mouse model shows potential for rapid identification of promising muscular dystrophy therapies
December 13, 2018 - Study reveals urban and rural differences in prenatal exposure to essential and toxic elements
December 13, 2018 - New collaborative partnership in quest of novel antibiotics
December 13, 2018 - Single tau molecule holds clues to help diagnose neurodegeneration in its earliest stages
December 13, 2018 - AHA Scientific Statement: Low Risk of Side Effects for Statins
December 13, 2018 - What Is Acute Flaccid Myelitis?
December 13, 2018 - How bereaved people control their thoughts without knowing it
December 13, 2018 - Health care democratization underway, according to 2nd annual Stanford Medicine Health Trends Report | News Center
December 13, 2018 - Going Beyond a Single Color
December 13, 2018 - London-based startup launches ‘thedrug.store’ aiming to clean up CBD industry
December 13, 2018 - Loss of tight junction barrier protein results in gastric cancer development
December 13, 2018 - Novel way to efficiently deliver anti-parasitic medicines
December 13, 2018 - RKI publishes new data on disease prevention and utilization of medical services
December 13, 2018 - High-tech, flexible patches sewn into clothes could help to stay warm
December 13, 2018 - The CCA releases three reports on requests for medical assistance in dying
December 13, 2018 - Restoring Hair Growth on Scarred Skin? Mouse Study Could Show the Way
December 13, 2018 - Probiotic use may reduce antibiotic prescriptions, researchers say
December 13, 2018 - Drug repositioning strategy identifies potential new treatments for epilepsy
December 13, 2018 - Chronic rhinitis associated with hospital readmissions for asthma and COPD patients
December 13, 2018 - Food poisoning discovery could save lives
December 13, 2018 - Cloned antibodies show potential to treat, diagnose life-threatening fungal infections
December 13, 2018 - Exercise may reduce colorectal cancer risk after weight loss
December 13, 2018 - Russian scientists create hardware-information system for brain disorders treatment
December 13, 2018 - Moderate alcohol consumption linked with lower risk of hospitalization
December 13, 2018 - Nurturing Healthy Neighborhoods | NIH News in Health
December 13, 2018 - Rise in meth and opioid use during pregnancy
December 13, 2018 - Researchers gain new insights into pediatric tumors
December 13, 2018 - FSU study finds racial disparity among adolescents receiving flu vaccine
December 13, 2018 - Study investigates attitudes toward implementation of ‘sex as a biological variable’ policy
December 13, 2018 - Drug cocktail induces cancer cell death by switching off energy supply
December 13, 2018 - Baculovirus virion completely eliminates liver-stage parasites in mouse model
December 13, 2018 - Researchers create noninvasive technology that detects when nerve cells fire
December 13, 2018 - Allen Institute for Immunology to partner with CU Anschutz to understand dynamics of human immune system
December 13, 2018 - Inability to do daily living tasks delays discharge of mental health patients
December 13, 2018 - Treating patients with hypertension induced albuminuria
December 13, 2018 - New substance could improve efficacy of established breast cancer treatments
December 13, 2018 - Scientists develop new stem cell line to study conversion of stem cells into muscle
December 13, 2018 - Re-programming the body’s energy pathway boosts kidney self-repair
December 13, 2018 - Research findings could help improve treatment of anxiety and post-traumatic stress disorders
December 13, 2018 - The Microbiome Movement announce Microbiotica as official industry partner
December 13, 2018 - New study reveals potential benefits of cEEG monitoring for infant ICU patients
December 13, 2018 - Whole-body imaging PET/MRI offers information to guide treatment options for prostate cancer
December 13, 2018 - International investigators fight against the negative campaign on benzodiazepines
December 13, 2018 - Targeting biochemical pathway may lead to new therapies for alleviating symptoms of anxiety disorders
December 13, 2018 - FDA Approves Tolsura (SUBA®-itraconazole capsules) for the Treatment of Certain Fungal Infections

U.S. Strikes to Avert Scarcity of Yellow Fever Vaccine

image_pdfDownload PDFimage_print

FRIDAY, April 28, 2017 — As a brand new outbreak of mosquito-borne yellow fever continues to develop in Brazil, U.S. well being officers say they are taking steps to avert any scarcity of vaccine vacationers may want.

On Friday, the U.S. Facilities for Illness Regulate and Prevention defined plans to “make certain a continuing yellow fever vaccine provide in the US,” as a result of present stockpiles are anticipated to be depleted through mid-2017.

The CDC identified that during 2016, Sanofi Pasteur, the maker of the YF-VAX shot towards yellow fever, was once pressured to curb manufacturing of the vaccine because of “a producing factor.”

“No yellow fever vaccine is anticipated to be to be had through mid-2017,” the CDC mentioned in a information unlock. “YF-VAX is the one yellow fever vaccine authorized to be used in the US and is shipped to roughly four,000 health center websites.”

On the other hand, a 2d yellow fever vaccine, known as Stamaril, will probably be made to be had at 250 clinics national, the CDC mentioned. Stamaril is manufactured in France through Sanofi Pasteur.

“As a result of yellow fever is a doubtlessly severe illness, CDC and Sanofi Pasteur collaborated on a plan to distribute restricted amounts of Stamaril yellow fever vaccine to forestall other people from changing into inflamed through the virus till manufacturing of YF-VAX resumes at a brand new facility in 2018,” the company defined.

U.S. well being officers have just lately sounded the alarm over yellow fever.

In an essay printed April 13 within the New England Magazine of Drugs, Dr. Anthony Fauci, director of the U.S. Nationwide Institute of Hypersensitivity and Infectious Illnesses, and colleague Dr. Catharine Paules mentioned that an enormous outbreak of yellow fever in Brazil should be intently monitored.

Yellow fever has a fairly prime demise charge and “is essentially the most critical [insect-transmitted] virus ever to flow into within the Americas,” Fauci and Paules wrote.

“Despite the fact that it’s extremely not likely that we will be able to see yellow fever outbreaks within the continental United States . . . it’s conceivable that travel-related instances of yellow fever may happen, with temporary classes of native transmission in hotter areas such because the Gulf Coast states, the place A. aegypti mosquitoes are prevalent,” the workforce added.

In keeping with the infectious illness mavens, yellow fever has the possible to be the 5th mosquito-borne an infection to seem within the continental United States because the 1990s, following dengue, West Nile, chikungunya and the Zika virus.

Yellow fever is possibly essentially the most bad of the ones 5, on the other hand. In a single outbreak that started within the Congo in December 2015, there have been 137 deaths amongst 961 showed instances, the file famous.

And within the present Brazilian outbreak, there have to this point been loads of instances and dozens of showed deaths, in step with well being government.

Extra ominous within the Brazilian outbreak is the truth that the sickness seems to be shifting from its conventional rural atmosphere in opposition to the towns.

“The outbreak is affecting spaces in shut proximity to primary city facilities [in Brazil] the place yellow fever vaccine isn’t robotically administered,” Fauci and Paules warned.

The authors stressed out that there is no proof but that mosquitoes are transmitting yellow fever between inflamed other people. On the other hand, the arrival of outbreaks close to city facilities “raises worry that, for the primary time in many years, city transmission of yellow fever will happen in Brazil,” they defined.

The illness isn’t a whole stranger to the US, even if scientists say the final primary outbreak lies a long way again in historical past.

“The Philadelphia yellow fever epidemic of 1793, as an example, killed roughly 10 % of the town’s inhabitants,” Fauci and Paules famous.

Fortuitously for American citizens nowadays, the yellow fever vaccine — first evolved in 1937 — is efficacious in combating sickness. The present vaccine is considered 99-percent efficient over an entire life.

For the ones already inflamed, it is an important that signs are noticed early.

On the other hand, “early popularity could also be tough in international locations similar to the US, the place maximum physicians have by no means noticed a case of yellow fever,” the authors identified. Early signs come with a fever that may mimic flu, adopted through a duration of remission, after which a level known as “intoxication” — prime fever, liver disorder and jaundice, or even kidney failure, center and frightened device disorder, and surprise.

No such instances have emerged in the US, however world journey approach unvaccinated other people may carry the sickness again house after visiting a deadly disease space.

The yellow fever outbreak comes because the Zika virus continues to have an effect on international locations all over the Americas. Each viruses are unfold through the similar mosquito species.

To forestall the Brazil outbreak from spreading, “early identity of instances and fast implementation of public well being control and prevention methods, similar to mosquito keep an eye on and suitable vaccination, are essential,” Fauci and Paules concluded.

Additional information

The U.S. Facilities for Illness Regulate and Prevention has extra on yellow fever.

Posted: April 2017

Really helpful for you

View feedback

Tagged with:

About author

Related Articles