Breaking News
October 23, 2018 - SLU researcher seeks to find solutions for ‘chemo brain’ symptoms and side effects of opioids
October 23, 2018 - Plastics now commonly found in human stools
October 23, 2018 - Zoledronic acid increases disease-free survival in premenopausal women with HR+ early breast cancer
October 23, 2018 - Cancer survivors at risk for heart failure during, after pregnancy
October 23, 2018 - Stanford project brings health education videos to mothers in South Africa
October 23, 2018 - HIV-infected Hispanics at higher risk of developing HPV-related cancers, finds study
October 23, 2018 - Politicians hop aboard ‘Medicare-for-all’ train, destination unknown
October 23, 2018 - Study suggests rising childhood obesity rates as cause for serious hip disease in adolescents
October 23, 2018 - Study highlights existence of barriers to early clinical trial access for adolescents and young adults
October 23, 2018 - Protein sequencing technique could revolutionize biomedical research
October 23, 2018 - Canon Medical to showcase world’s first Ultra-High Resolution CT system at ASTRO 2018
October 23, 2018 - Spectrum Pharmaceuticals Announces Release of Updated Poziotinib Data From MD Anderson Phase 2 Study in Non-Small Cell Lung Cancer Patients
October 23, 2018 - Cancer stem cells use ‘normal’ genes in abnormal ways
October 23, 2018 - Bad Blood: A conversation with investigative reporter John Carreyrou | News Center
October 23, 2018 - As U.S. fertility rates collapse, finger-pointing and blame follow
October 23, 2018 - Researchers develop promising targeted strategy to treat chemo-resistant blood cancer
October 23, 2018 - Pilot clinical trial shows effectiveness of bioelectronic medicine device for lupus
October 23, 2018 - Genentech’s combination therapy improves outcome in patients with non-squamous non-small cell lung cancer
October 23, 2018 - 11th World Stroke Congress examines high stroke impact in low- and middle-income countries
October 22, 2018 - Breast cancer survival could be extended with two new drug combinations
October 22, 2018 - Researchers discover how acne-causing bacteria resist treatment
October 22, 2018 - Cancer trial shows treating the prostate with radiotherapy improves survival
October 22, 2018 - New hope for a drug to treat lymphedema symptoms
October 22, 2018 - Immune-Based Treatment Helps Fight Aggressive Breast Cancer, Study Finds
October 22, 2018 - Takeda announces positive Phase 3 ALTA-1L data in first-line therapy for advanced ALK+ NSCLC
October 22, 2018 - Paternal exercise has significant impact on child’s lifelong metabolic health
October 22, 2018 - Targeting specific genomic mutation in breast cancer improves survival
October 22, 2018 - Loss of tumor protein p53 helps cancer cells grow in hostile environment
October 22, 2018 - IDT to demonstrate CRISPR expertise at European-focused events
October 22, 2018 - Breathing through the nose improves memory consolidation
October 22, 2018 - Recreational Marijuana Now Legal in Canada
October 22, 2018 - Scientists reveal drumming helps schoolchildren diagnosed with autism
October 22, 2018 - A stage IV cancer patient discusses what it means to live well with serious illness
October 22, 2018 - In Kids with Autism, Short Questionnaire May Detect GI Disorders
October 22, 2018 - Innovative strategy opens up new avenue of treatment for anthrax infections
October 22, 2018 - Merck presents MK-1454 Phase 1 data for treatment of advanced solid tumors or lymphomas
October 22, 2018 - Aspirin may be effective in preventing blood clots after knee replacement
October 22, 2018 - Drug cocktail that increases lifespan discovered
October 22, 2018 - Gilead Sciences presents Phase 3 results of filgotinib in biologic-experienced rheumatoid arthritis at 2018 ACR/ARHP Annual Meeting
October 22, 2018 - Study shows potential positive impact of group prenatal care on birth outcomes
October 22, 2018 - Immunotherapy with pembrolizumab extends survival in metastatic or recurrent head and neck cancer
October 22, 2018 - Health Tip: Keep Ticks Away
October 22, 2018 - Obsessive-compulsive disorder – Genetics Home Reference
October 22, 2018 - Researchers find disrupted functional connectivity in cerebellum of adults with HF-ASD
October 22, 2018 - Deciphera presents Phase 1 clinical results of DCC-2618 in patients with gastrointestinal stromal tumors
October 22, 2018 - Combination of Opdivo and Yervoy shows four-year survival benefits in patients with advanced melanoma
October 22, 2018 - Overcoming bottlenecks in early drug discovery with the power of sound
October 22, 2018 - Scientists discover genes that contribute to ADHD development
October 22, 2018 - Incyte announces Phase 2 FIGHT-202 trial data in patients with cholangiocarcinoma
October 22, 2018 - FDA approves update to Rituxan label to include information on treatment of rare forms of vasculitis
October 22, 2018 - At-home biofeedback therapy effective in relieving difficult-to-treat constipation
October 22, 2018 - Merck presents KEYNOTE-057 trial results for patients with high-risk non-muscle invasive bladder cancer
October 22, 2018 - People with periodontal disease less likely to reach healthy blood pressure ranges
October 22, 2018 - Phase III LONSURF study shows progression-free survival in patients with refractory metastatic gastric cancer
October 22, 2018 - Primary care doctors ‘not doing enough’ to curb STDs
October 22, 2018 - Pfizer announces PALOMA-3 trial results in patients with HR+, HER2- metastatic breast cancer
October 22, 2018 - ImmunoGen announces study results of platinum-resistant ovarian cancer therapy at ESMO 2018 Congress
October 22, 2018 - Study findings could set new standard of care for advanced anal cancer
October 22, 2018 - Erlotinib improves progression-free survival in EGFR mutated NSCLC
October 22, 2018 - Pain, insomnia, and depression often drive osteoarthritis patients to seek medical care
October 22, 2018 - The International Society of Refractive Surgery honors Vivior Chairman with Casebeer Award
October 22, 2018 - Multi-strain probiotic helps reduce chemotherapy-induced diarrhea in cancer patients
October 22, 2018 - Study shows potential of avelumab plus axitinib as new treatment option for patients with advanced RCC
October 22, 2018 - Vertex gets European CHMP positive opinion for KALYDECO to treat patients with cystic fibrosis
October 22, 2018 - Phase III trial reports positive results with HDAC inhibitor in advanced breast cancer patients
October 22, 2018 - Prostate radiotherapy improves survival in men with low burden of metastatic disease
October 22, 2018 - Duration of respiratory disturbances may better predict mortality risk from OSA
October 22, 2018 - Free phone app helps low-income obese patients to lose weight
October 22, 2018 - Immunotherapy with nivolumab and ipilimumab may improve survival in patients with MSI-high metastatic colorectal cancers
October 22, 2018 - FOTIVDA expected to be included in new ESMO guidelines for advanced renal cell carcinoma
October 22, 2018 - Compression Collar May Protect Brain of Female Soccer Players
October 22, 2018 - Technique visualizes neuron communication
October 22, 2018 - Advancement in medical imaging methods for health care
October 22, 2018 - Takeda presents vedolizumab phase 3 VISIBLE 1 trial results for treatment of moderately to severely active ulcerative colitis
October 22, 2018 - Immunotherapy increases survival in some patients with metastatic triple negative breast cancer
October 22, 2018 - Exelixis presents CABOSUN and METEOR trial results in patients with advanced renal cell carcinoma
October 22, 2018 - LYNPARZA Phase III SOLO-1 results show improved outcome for patients with advanced BRCA-mutated ovarian cancer
October 22, 2018 - Brainlab unveils ExacTrac Dynamic at ASTRO meeting in San Antonio, Texas
October 22, 2018 - Not exercising is worse than smoking, diabetes or heart disease finds study
October 22, 2018 - Shorter course of trastuzumab could be an option for women with HER2+ early breast cancer
LGBQ adolescents at much greater risk of suicide than heterosexual counterparts

LGBQ adolescents at much greater risk of suicide than heterosexual counterparts

image_pdfDownload PDFimage_print
Credit: CC0 Public Domain

Adolescents who identify as gay, lesbian, bisexual or questioning are much more likely to consider, plan or attempt suicide than their heterosexual peers, according to research from the University of Pennsylvania, the University of California, San Diego, and San Diego State University published this week in the Journal of the American Medical Association.

Specifically, of a nationally representative sample of 15,624 high-school age participants, 40 percent of sexual-minority adolescents seriously considered suicide compared to 15 percent of their heterosexual counterparts. Nearly a quarter attempted suicide compared to approximately 6 percent of those in the sexual majority.

“The most staggering finding, the one that really makes you think, is just how prevalent these suicide-risk behaviors are in the LGBQ adolescent community,” said Theodore L. Caputi, who conducted this work while at Penn’s Wharton School and who is now a pursuing a master’s degree at University College Cork in Ireland. “Research has shown that suicide-risk behaviors are an indicator of extreme distress.”

Caputi’s research focuses mostly on substance-use disorders like the opioid epidemic and teenage drug use. During a fellowship in Wharton’s Summer Program for Undergraduate Research, while investigating the intersection of minority groups, substance use and mental-health disorders, he noticed a gap in the literature.

“The more I researched the connection between suicide risk and teens who identify as sexual minorities, the more interesting it became,” he said. “In particular, these results were so striking it was clear this work could have some real-world impact informing policy.”

He teamed up with Davey Smith, a professor at the UC San Diego School of Medicine, and John Ayers, an adjunct associate professor in the San Diego State Graduate School of Public Health. From there, the trio began digging deep into data from the National Youth Behavioral Risk Survey administered by the Centers for Disease Control and Prevention.

This survey, which began in 1990 and was most recently given in 2015, asks high-school students about their conduct in a range of areas, from smoking to exercise. It gets specific about topics like gun-carrying and electronic bullying, alcohol use and suicide. For this research, that last category proved thought-provoking, particularly questions related to suicidal thoughts and actions.

To analyze the data, Caputi and colleagues used a new methodology focused on risk ratios rather than odds ratios. The researchers showed the probability of a link between sexual-minority groups and suicide risk and then drew a comparison to the relevant heterosexual groups. They also concentrated on adolescents, a subset rarely before explored in this context.

The team noticed several important trends: Though female sexual-minority adolescents, on the whole, show a higher absolute prevalence for suicide-risk behaviors, when the researchers incorporated in statistics from heterosexual counterparts, sexual-minority males were at greater relative risk. For behaviors such as trying to take their own lives, LGBQ males were almost five times as likely to report having done so than heterosexual males in the same age group.

Another trend stuck out, one related to adolescents who identify as bisexual. Nearly one-third of this group reported attempting suicide in the past 12 months, and 46 percent had considered it. Previous research has revealed that bisexual adolescents in particular experience great distress because some people are dismissive of this sexual orientation.

“There are clearly differences in how sexual-minority adolescents experience the world,” Caputi said. “External stressors like stigma and isolation are significant contributing factors, and those weigh on members of these high-risk communities.”

Though the researchers acknowledge some limitations with the study, for example, a lack of data about transgender people and just a 60-percent response rate to the survey, they hope their results call attention to the severity of this problem and prompt action on the part of policymakers, community members, educators and clinicians.

“If people are thinking about suicide and their attempts are not successful, that does not mean we’ve won,” Caputi said. “The goal is to decrease the stressors that cause LGBQ adolescents to contemplate suicide in the first place. We’re hoping our study will inspire social and policy changes that lead to happier and healthier lives for LGBQ adolescents.”


Explore further:
Same-sex marriage legalization linked to reduction in suicide attempts among teens

More information:
Journal of the American Medical Association (2017). jamanetwork.com/journals/jama/ … 1001/jama.2017.16908

Journal reference:
Journal of the American Medical Association

Provided by:
University of Pennsylvania

Tagged with:

About author

Related Articles