Porvair Sciences recently released a new, high-performance Chromatrap® ChIP-Seq kit (v.1.5) that is optimized to work from fresh and frozen extracted tissue, as well as cell lines.
This latest version of the popular Chromatrap® ChIP-Seq kit enables ChIP to be performed using as little as 50mg of a wide range of extracted tissue samples. The new protocol incorporates optimised lysis and hypotonic buffers and guidelines on how to achieve maximum extraction of chromatin from limited sample quantities.
This ground-breaking technology that delivers great results whilst saving precious samples is supported by a number of recent research publications.
Chromatrap® ChIP-Seq kits utilise a proprietary solid-state technology to deliver a streamlined ChIP-Seq protocol from small cell numbers and low chromatin concentrations.
Specifically adapted for broader chromatin concentrations, Chromatrap ChIP-Seq combines the dynamic range of Chromatrap® with the downstream analysis power of deep sequencing. This allows faster, more reproducible genome wide identification of transcription factor binding sites and specific DNA associated protein modifications.
The kit is ideal for more difficult primary cell samples and for the enrichment of low abundant transcription factors.
Chromatrap is a business unit of Porvair Sciences Ltd. Their extensive product range includes ChIP kits, DNA clean up kits and other innovative products for epigenetic research. Now cited in approaching thirty papers, Chromatrap® ChIP technology is rapidly becoming the method of choice for fast accurate ChIP assays.