Breaking News
January 19, 2019 - Drinking soft drinks while exercising in hot weather may increase risk of kidney disease
January 19, 2019 - Formlabs 3D prints anatomical models
January 19, 2019 - Heart-Healthy Living Also Wards Off Type 2 Diabetes
January 19, 2019 - Teaching Kids to Be Smart About Social Media (for Parents)
January 19, 2019 - Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease
January 19, 2019 - Researchers examine how spray from showers and toilets expose us to disease causing bacteria
January 19, 2019 - Behavioral experiments confirm that additional neurons improve brain function
January 19, 2019 - New study compares performance of real-time infectious disease forecasting models
January 19, 2019 - Obesity can be risk factor for developing renal cell carcinoma, confirms study
January 19, 2019 - New regulation designs on cigarette packs direct smokers’ attention to health warnings
January 19, 2019 - QIAGEN receives first companion diagnostic approval in Japan
January 19, 2019 - Study explores role of Dunning-Kruger effect in anti-vaccine attitudes
January 19, 2019 - Newly identified subset of immune cells may be key to fighting chronic inflammation
January 19, 2019 - New immune response regulators discovered
January 18, 2019 - Poor blood oxygenation during sleep predicts chance of heart-related death
January 18, 2019 - First international consensus on the diagnosis and management of fibromuscular dysplasia
January 18, 2019 - Rapid resistance gene sequencing technology can hasten identification of antibiotic-resistant bacteria
January 18, 2019 - Researchers develop artificial enzymatic pathway for synthesizing isoprenoids in E. coli
January 18, 2019 - Scientists advise caution in immunotherapy research
January 18, 2019 - How children across the world develop language
January 18, 2019 - Columbia Medical Student Receives McDonogh Scholarship
January 18, 2019 - Secretive ‘Rebate Trap’ Keeps Generic Drugs For Diabetes And Other Ills Out Of Reach
January 18, 2019 - Plant based diet could be the best option for the planet says commission
January 18, 2019 - New conservation practice could reduce nitrogen from agricultural drainage, study shows
January 18, 2019 - UIC researchers receive $1.7 million NCI grant to study Southeast Asian fruit
January 18, 2019 - New study determines the fate of DNA derived from genetically modified food
January 18, 2019 - Scientists develop new gene therapy that prevents axon destruction in mice
January 18, 2019 - Study finds critically low HPV vaccination rates among younger adolescents in the U.S.
January 18, 2019 - Brain cells involved in memory play key role in reducing future eating behavior
January 18, 2019 - Risk for Conversion of MS Varies With Different Therapies
January 18, 2019 - Investigational cream may help patients with inflammatory skin disease
January 18, 2019 - Medical school news office receives six writing awards | News Center
January 18, 2019 - County By County, Researchers Link Opioid Deaths To Drugmakers’ Marketing
January 18, 2019 - Research reveals risk for developing more than one mental health disorder
January 18, 2019 - Scientists discover a dramatic pattern of bone growth in female mice
January 18, 2019 - Study finds link between lengthy periods of undisturbed maternal sleep and stillbirths
January 18, 2019 - New nuclear medicine method could improve detection of primary and metastatic melanoma
January 18, 2019 - Combination therapy shows high efficacy in treating people with leishmaniasis and HIV
January 18, 2019 - Health Tip: Don’t Ignore Changes in Skin Color
January 18, 2019 - Dietary Recommendations for Healthy Children
January 18, 2019 - Eliminating the latent reservoir of HIV
January 18, 2019 - Pain From The Government Shutdown Spreads. This Time It’s Food Stamps
January 18, 2019 - Newly discovered regulatory mechanism helps control fat metabolism
January 18, 2019 - New rapid blood tests could speed up TB diagnosis, save the NHS money
January 18, 2019 - Researchers develop intelligent system for ‘tuning’ powered prosthetic knees
January 18, 2019 - Monoclonal antibody pembrolizumab prolongs survival in patients with squamous cell carcinoma
January 18, 2019 - New research detects mosquito known to transmit malaria for the first time in Ethiopia
January 18, 2019 - New guidelines to make swallowing safer for people in Australian nursing homes
January 18, 2019 - Lumex Instruments’ RA-915AM monitor installed at Hg treatment plant in Almadén, Spain
January 18, 2019 - ACCC survey finds multiple threats to growth of cancer programs
January 18, 2019 - Meeting the challenge of engaging men in HIV prevention and treatment
January 18, 2019 - Furloughed Feds’ Health Coverage Intact, But Shutdown Still Complicates Things
January 18, 2019 - Experts discuss various aspects on health risks posed by fumigated containers
January 18, 2019 - Researchers use gene-editing tool CRISPR/Cas9 to limit impact of parasitic diseases
January 18, 2019 - Alpha neurofeedback training could be a means of enhancing learning success
January 18, 2019 - Innovative ‘light’ method demonstrates positive results in fight against malignant tumors
January 18, 2019 - The cytoskeleton of neurons found to play role in Alzheimer’s disease
January 18, 2019 - New resource-based approach to improve HIV care in low- and middle-income countries
January 18, 2019 - Bedfont appoints Dr Jafar Jafari as first member of the Gastrolyzer Medical Advisory Board
January 18, 2019 - New study shows link between secondhand smoke and cardiac arrhythmia
January 18, 2019 - DZIF scientists reveal problems with available diagnostics for Zika and chikungunya virus
January 18, 2019 - Breast cancers more likely to metastasize in young women within 10 years of giving birth
January 18, 2019 - Over 5.6 million Americans exposed to high nitrate levels in drinking water
January 18, 2019 - Blood vessels can now be created perfectly in a petri dish
January 18, 2019 - Study identifies prominent socioeconomic and racial disparities in health behavior in Indiana
January 18, 2019 - Young-Onset Type 2 Diabetes Tied to Increased Hospitalization Risk
January 18, 2019 - For-profit nursing schools associated with lower performance on nurse licensure test
January 18, 2019 - Considering the culture of consent in medicine
January 18, 2019 - Researchers identify comprehensive guidelines for managing severe atopic dermatitis
January 18, 2019 - Analyzing proteins in blister fluid may classify burn severity more accurately
January 18, 2019 - Study finds higher suicide rates among youth who were Medicaid enrollees
January 18, 2019 - Opioid drugs often overprescribed to children for pain relief, say CHOP surgeons
January 18, 2019 - New biodegradable wound dressing material accelerates healing
January 18, 2019 - Life in Space May Take Toll on Spinal Muscles
January 18, 2019 - Bulldogs’ screw tails linked to human genetic disease
January 18, 2019 - Immunotherapy target identified for pediatric cancers
January 18, 2019 - Financial stress may increase heart disease risk in African Americans
January 18, 2019 - Scientists solve another piece of Ebola virus puzzle
January 18, 2019 - New project finds how endocrine disruptors interfere with thyroid functions
January 18, 2019 - Research finds decline in ketone body utilization when coronary circulation is reduced
Healthy Diet, Physical Activity Limit Excess Weight Gain During Pregnancy

Healthy Diet, Physical Activity Limit Excess Weight Gain During Pregnancy

image_pdfDownload PDFimage_print

Source: Getty Images

Women who are overweight before pregnancy can use diet modification and physical activity to safely limit excessive weight gain during pregnancy, according to the combined results from seven NIH-funded randomized controlled clinical trials, including one led by researchers at Columbia University Irving Medical Center.

Excessive weight gain during pregnancy may have multiple effects on the health of the mother and the child. It can increase a woman’s risk of developing diabetes and hypertensive disorders and of delivery by cesarean section and has been associated with childhood obesity and diabetes. Women carrying extra weight before becoming pregnant are more likely to exceed the CDC’s recommended weight gain—15 to 25 pounds for women who are overweight and 11 to 20 pounds for those with obesity—and further increase the risk of complications. (For women who start out at a normal weight, the recommended weight gain is 25 to 35 pounds.)

Women can control the amount of weight gained during the second and third trimesters of pregnancy using a healthy lifestyle approach.

The trials enrolled a total of 1,150 women with overweight or obesity in the first or second trimester of pregnancy. Half of the group took part in a diet modification and/or physical activity program to prevent excess weight gain during pregnancy.

On average, the women enrolled in a weight-control program gained less weight—about 4 pounds less—than those who were not enrolled. About 38 percent of the women enrolled in weight-control programs gained the recommended amount of weight versus 25 percent of the women in the control group. However, both groups had similar rates of diabetes, hypertension, preeclampsia, and C-sections.

The results were published Sept. 6 in the journal Obesity.

“These findings show that women can control the amount of weight gained during the second and third trimesters of pregnancy using a healthy lifestyle approach,” says Dympna Gallagher, EdD, professor of nutritional medicine at Columbia University Vagelos College of Physicians and Surgeons and an investigator in the clinical trials research group, Lifestyle Interventions for Expectant Moms (LIFE-Moms). “Had the intervention started earlier in pregnancy, such as at the beginning of the first trimester, the impact on limiting excessive weight gain and maternal complications may have been greater.”

Gallagher and Xavier Pi-Sunyer, MD, led the trial at CUIMC that investigated whether intervening to prevent excess weight gain during pregnancy would have an effect on a newborn’s body composition. The CUIMC study, published earlier this year in Obesity, included 210 healthy women with overweight or obesity; half were enrolled in a program that promoted a healthier diet and increased physical activity during the second and third trimesters.

Babies of women enrolled in the diet and physical activity program weighed more at birth than babies of the controls. And though babies in both groups had similar amounts of body fat, babies from the lifestyle intervention group had more lean body mass and bigger heads, suggesting increased brain development.

Longer-term studies are needed, Gallagher says, to determine if having more lean mass at birth benefits the babies later in life.

“Interestingly, we did not find an association between infant lean mass and weight gain during pregnancy, either excessive or within guidelines,” Gallagher says. “This suggests that aspects of the diet and physical activity program other than limiting weight gain may be important for the development of babies with lean mass.”

Dympna Gallagher, EdD, is a professor of nutritional medicine at Columbia University Vagelos College of Physicians and Surgeons and in Columbia’s Institute of Human Nutrition.

 

Xavier Pi-Sunyer, MD, is a professor of medicine at Columbia University Vagelos College of Physicians and Surgeons.

 

Additional authors of the CUIMC-led study include Barak Rosenn (Mount Sinai West), Tatiana Toro-Ramos (Columbia), Charles Paley (Mount Sinai West), Sonia Gidwani (Cook Children’s Medical Center, Fort Worth, TX), Michelle Horowitz (Columbia), Janet Crane (Columbia), Susan Lin (Columbia), John C. Thornton (Thornton Consulting, Mahopac, NY).

 

Women in the Columbia-led study were recruited from the obstetrics and pediatrics departments at Mount Sinai West.

 

The study was funded by the NIH (U01‐DK094463, P30‐DK026687, T32‐DK007559, U01-DK094418, U01-DK094416, 5U01-DK094466, U01-HL114344, U01-HL114377), the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the Indian Health Service.

Tagged with:

About author

Related Articles