Breaking News
May 3, 2019 - Vaping and Smoking May Signal Greater Motivation to Quit
May 3, 2019 - Dementia looks different in brains of Hispanics
May 3, 2019 - Short-Staffed Nursing Homes See Drop In Medicare Ratings
May 3, 2019 - Study of teens with eating disorders explores how substance users differ from non-substance users
May 3, 2019 - Scientists develop new video game that may help in the study of Alzheimer’s
May 3, 2019 - Arc Bio introduces Galileo Pathogen Solution product line at ASM Clinical Virology Symposium
May 3, 2019 - Cornell University study uncovers relationship between starch digestion gene and gut bacteria
May 3, 2019 - How to Safely Use Glucose Meters and Test Strips for Diabetes
May 3, 2019 - Anti-inflammatory drugs ineffective for prevention of Alzheimer’s disease
May 3, 2019 - Study tracks Pennsylvania’s oil and gas waste-disposal practices
May 3, 2019 - Creating a better radiation diagnostic test for astronauts
May 3, 2019 - Vegans are often deficient in these four nutrients
May 3, 2019 - PPDC announces seed grants to develop medical devices for children
May 3, 2019 - Study maps out the frequency and impact of water polo head injuries
May 3, 2019 - Research on Reddit identifies risks associated with unproven treatments for opioid addiction
May 3, 2019 - Good smells may help ease tobacco cravings
May 3, 2019 - Medical financial hardship found to be very common among people in the United States
May 3, 2019 - Researchers develop multimodal system for personalized post-stroke rehabilitation
May 3, 2019 - Study shows significant mortality benefit with CABG over percutaneous coronary intervention
May 3, 2019 - Will gene-editing of human embryos ever be justifiable?
May 3, 2019 - FDA Approves Dengvaxia (dengue vaccine) for the Prevention of Dengue Disease in Endemic Regions
May 3, 2019 - Why Tonsillitis Keeps Coming Back
May 3, 2019 - Fighting the opioid epidemic with data
May 3, 2019 - Maggot sausages may soon be a reality
May 3, 2019 - Deletion of ATDC gene prevents development of pancreatic cancer in mice
May 2, 2019 - Targeted Therapy Promising for Rare Hematologic Cancer
May 2, 2019 - Alzheimer’s disease is a ‘double-prion disorder,’ study shows
May 2, 2019 - Reservoir bugs: How one bacterial menace makes its home in the human stomach
May 2, 2019 - Clinical, Admin Staff From Cardiology Get Sneak Peek at Epic
May 2, 2019 - Depression increases hospital use and mortality in children
May 2, 2019 - Vicon and NOC support CURE International to create first gait lab in Ethiopia
May 2, 2019 - Researchers use 3D printer to make paper organs
May 2, 2019 - Viral infection in utero associated with behavioral abnormalities in offspring
May 2, 2019 - U.S. Teen Opioid Deaths Soaring
May 2, 2019 - Opioid distribution data should be public
May 2, 2019 - In the Spotlight: “I’m learning every single day”
May 2, 2019 - 2019 Schaefer Scholars Announced
May 2, 2019 - Podcast: KHN’s ‘What The Health?’ Bye-Bye, ACA, And Hello ‘Medicare-For-All’?
May 2, 2019 - Study describes new viral molecular evasion mechanism used by cytomegalovirus
May 2, 2019 - SLU study suggests a more equitable way for Medicare reimbursement
May 2, 2019 - Scientists discover first gene involved in lower urinary tract obstruction
May 2, 2019 - Researchers identify 34 genes associated with increased risk of ovarian cancer
May 2, 2019 - Many low-income infants receive formula in the first few days of life, finds study
May 2, 2019 - Global study finds high success rate for hip and knee replacements
May 2, 2019 - Taking depression seriously: What is it?
May 2, 2019 - With Head Injuries Mounting, Will Cities Put Their Feet Down On E-Scooters?
May 2, 2019 - Scientists develop small fluorophores for tracking metabolites in living cells
May 2, 2019 - Study casts new light into how mothers’ and babies’ genes influence birth weight
May 2, 2019 - Researchers uncover new brain mechanisms regulating body weight
May 2, 2019 - Organ-on-chip systems offered to Asia-Pacific regions by Sydney’s AXT
May 2, 2019 - Adoption of new rules drops readmission penalties against safety net hospitals
May 2, 2019 - Kids and teens who consume zero-calorie sweetened beverages do not save calories
May 2, 2019 - Improved procedure for cancer-related erectile dysfunction
May 2, 2019 - Hormone may improve social behavior in autism
May 2, 2019 - Alzheimer’s disease may be caused by infectious proteins called prions
May 2, 2019 - Even Doctors Can’t Navigate Our ‘Broken Health Care System’
May 2, 2019 - Study looks at the impact on criminal persistence of head injuries
May 2, 2019 - Honey ‘as high in sugars as table sugar’
May 2, 2019 - Innovations to U.S. food system could help consumers in choosing healthy foods
May 2, 2019 - FDA Approves Mavyret (glecaprevir and pibrentasvir) as First Treatment for All Genotypes of Hepatitis C in Pediatric Patients
May 2, 2019 - Women underreport prevalence and intensity of their own snoring
May 2, 2019 - Concussion summit focuses on science behind brain injury
May 2, 2019 - Booker’s Argument For Environmental Justice Stays Within The Lines
May 2, 2019 - Cornell research explains increased metastatic cancer risk in diabetics
May 2, 2019 - Mount Sinai study provides fresh insights into cellular pathways that cause cancer
May 2, 2019 - Researchers to study link between prenatal pesticide exposures and childhood ADHD
May 2, 2019 - CoGEN Congress 2019: Speakers’ overviews
May 2, 2019 - A new strategy for managing diabetic macular edema in people with good vision
May 2, 2019 - Sagent Pharmaceuticals Issues Voluntary Nationwide Recall of Ketorolac Tromethamine Injection, USP, 60mg/2mL (30mg per mL) Due to Lack of Sterility Assurance
May 2, 2019 - Screen time associated with behavioral problems in preschoolers
May 2, 2019 - Hormone reduces social impairment in kids with autism | News Center
May 2, 2019 - Researchers synthesize peroxidase-mimicking nanozyme with low cost and superior catalytic activity
May 2, 2019 - Study results of a potential drug to treat Type 2 diabetes in children announced
May 2, 2019 - Multigene test helps doctors to make effective treatment decisions for breast cancer patients
May 2, 2019 - UNC School of Medicine initiative providing unique care to dementia patients
May 2, 2019 - Nestlé Health Science and VHP join forces to launch innovative COPES program for cancer patients
May 2, 2019 - Study examines how our brain generates consciousness and loses it during anesthesia
May 2, 2019 - Transition Support Program May Aid Young Adults With Type 1 Diabetes
May 2, 2019 - Study shows how neutrophils exacerbate atherosclerosis by inducing smooth muscle-cell death
May 2, 2019 - Research reveals complexity of how we make decisions
Pioneering software system hopes to make epilepsy surgery safer and easier

Pioneering software system hopes to make epilepsy surgery safer and easier

A team of researchers, clinicians and engineers from UCLH, UCL, King’s College London and the Epilepsy Society have developed a world-leading software system called EpiNav, which stands for epilepsy navigation, and their work is being featured on tonight’s episode of the BBC’s Trust Me I’m a Doctor.

Around half a million people in the UK suffer from epilepsy, a condition where abnormal electrical activity in the brain leads to recurrent seizures. The condition can be managed with anti-epileptic drugs, but up to 30% of patients don’t respond.

For these patients, another option is to undergo brain surgery to remove the part of the brain that is causing the seizures, but before this can be attempted the surgeons need to know exactly which parts of the brain are responsible. Often, this can only be determined through a complex procedure that involves temporarily implanting electrodes into the brain to measure the electrical activity.

Up to 16 electrodes could be required – all of which need to be positioned without damaging crucial blood vessels or vital parts of the brain such as those involved with speech, vision or movement. It’s extremely risky and challenging, so in many cases doctors and patients are reluctant to proceed.

The pioneering new approach hopes to make epilepsy surgery safer and easier. It is funded by the Wellcome Trust and the NIHR UCLH Biomedical Research Centre, and brings together CT scans and MRI scans of a patient’s brain to create an incredibly detailed 3D map that can be used to plan surgery with millimetre accuracy, calculating safe routes through the brain for each electrode that needs to be implanted. What’s more, the technology can be taken into the operating theatre to guide surgeons in real time.

Gabriel Weston met Prof John Duncan of the National Hospital for Neurology and Neurosurgery and Prof Sebastian Ourselin of King’s College London to find out more about this impressive new system.

Currently, EpiNav is being tested in an ongoing clinical trial where in half of the surgeries the procedure is being performed entirely manually by NHNN surgeons Andrew McEvoy, Anna Miserocchi, and UCL clinical researcher Vejay Vakharia.

In the other half, the EpiNav data is being passed to a robot which assists the surgeons by lining up the precise trajectory for each electrode. The researchers anticipate that the robot will help to make the process quicker and even more accurate, which in turn could make epilepsy surgery available to patients who may not previously been approved for the procedure.

The segment also follows the story of Alistair, who underwent a surgical resection after developing epilepsy as a child. In order to make sure he would be suitable for the procedure, Alistair first had a series of electrodes placed in his brain to measure the electrical signals in his brain. After monitoring this for a number of days in a controlled hospital environment, the clinical and technical specialists were able to pin-point the region of the brain responsible for his seizures which was removed in a second operation.

Both the diagnostic and interventional stage of the procedure are planned extremely carefully, making sure the risk of affecting an area of the brain responsible for key motor functions will not be affected – in many cases meaning patients are just not viable for this treatment.

Already, the EpiNav software has been used in over 150 epilepsy surgeries and the team anticipate that in future it will be integrated into operating theatres across the UK. This software could also have even wider applications in future, and could be used in other areas of neurosurgery to help treat conditions from brain tumours to Parkinson’s disease.

Tagged with:

About author

Related Articles