Breaking News
March 23, 2019 - The Current issue of “The view from here” is concerned with Cancer
March 23, 2019 - Mouse model validates how ‘good’ and ‘bad’ bacteria affect acne
March 23, 2019 - Individual amygdala neurons respond to touch, imagery and sounds
March 23, 2019 - Combination of two topical creams can prevent cancer
March 23, 2019 - Study suggests depression screening when assessing African-Americans for schizophrenia
March 23, 2019 - New electronic support system for choosing drug treatment based on patient’s genotype
March 23, 2019 - First-of-its-kind study provides pregnancy statistics of imprisoned U.S. women
March 23, 2019 - Marinus Pharmaceuticals Initiates Phase 3 Study in Children with PCDH19-Related Epilepsy
March 23, 2019 - Laparoscopy: MedlinePlus Lab Test Information
March 23, 2019 - Shellfish allergies: can they be treated?
March 23, 2019 - Toilet seat heart monitoring system
March 23, 2019 - Researchers identify way to improve common treatment for PTSD
March 23, 2019 - High potency cannabis use linked to psychosis finds study
March 23, 2019 - Evoke Pharma Submits Response to FDA Review Letter for Gimoti NDA
March 23, 2019 - Tracking HIV’s ever-evolving genome in effort to prioritize public health resources
March 23, 2019 - Scientists grow most sophisticated brain organoid to date
March 23, 2019 - ADHD drug raising risk of psychosis
March 22, 2019 - FDA approves brexanolone, first drug developed to treat postpartum depression
March 22, 2019 - Gruesome cat and dog experiments by the USDA exposed
March 22, 2019 - Ball pits used in children’s physical therapy may contribute to germ transmission
March 22, 2019 - Long-term use of inexpensive weight-loss drug may be safe and effective
March 22, 2019 - FDA Approves Sunosi (solriamfetol) for Excessive Daytime Sleepiness Associated with Narcolepsy or Obstructive Sleep Apnea
March 22, 2019 - Anti-Müllerian Hormone Test: MedlinePlus Lab Test Information
March 22, 2019 - Finding the right exercise, diet aids for HIV patients
March 22, 2019 - Health Plans For State Employees Use Medicare’s Hammer On Hospital Bills
March 22, 2019 - Researchers develop new tool for imaging large groups of neurons in living animals
March 22, 2019 - Certain bacteria and immune factors in vagina may cause or protect against preterm birth
March 22, 2019 - Novel breath test could pave new way to non-invasively measure gut health
March 22, 2019 - Pharmaceutical and personal care products may result in new contaminants in waterways
March 22, 2019 - ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib
March 22, 2019 - Wiedemann-Rautenstrauch syndrome – Genetics Home Reference
March 22, 2019 - Health insurance is not assurance of healthcare
March 22, 2019 - Supporting “curiosity-driven research” at the Discovery Innovation Awards
March 22, 2019 - Must-Reads Of The Week (Some Flying Below The Radar)
March 22, 2019 - Newly engineered nanoscale protein micelles can be tracked by MRI
March 22, 2019 - New model more effective in predicting risk of opioid overdose than traditional models
March 22, 2019 - Mayo Clinic study identifies potential new drug therapy for liver diseases
March 22, 2019 - Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD
March 22, 2019 - Early discharge does not increase readmission risk for patients after lung surgery
March 22, 2019 - Creating diverse pool of trained scientists to address Alzheimer’s research needs
March 22, 2019 - Surprising discovery offers clues to limit graft-vs.-host disease
March 22, 2019 - Study shows ACA’s positive impact on healthcare affordability and access for women
March 22, 2019 - Study provides new pathway for controlling inflammation
March 22, 2019 - New combination treatment shows promise for common brain tumor in children
March 22, 2019 - Virginia Tech Helmet Lab releases first youth-specific football helmet ratings
March 22, 2019 - New algae-based treatment could reduce need for limb amputation
March 22, 2019 - Stroke risk reduces in both black and white older Medicare beneficiaries, study reports
March 22, 2019 - City of Hope exhibits current studies and data on cancer therapies at AACR
March 22, 2019 - New study identifies CD40 molecule as key entry point for dangerous bacteria
March 22, 2019 - Health Tip: Six Steps to a Healthier Life
March 22, 2019 - even a little activity helps you live longer
March 22, 2019 - Many individuals recovering from addiction continue to suffer from chronic physical disease
March 22, 2019 - New drugs on PBS for Parkinson’s, MND and Cutaneous T cell lymphoma
March 22, 2019 - Saving energy also saves lives, UW-Madison study says
March 22, 2019 - Former inmates who receive social support have better mental health, study finds
March 22, 2019 - Nanofibrous membrane could enhance periodontal tissue regeneration
March 22, 2019 - Anti-vaxxer Italian leader down with chickenpox
March 22, 2019 - Servier collaborates with Harvard researchers to fight metabolic diseases
March 22, 2019 - National Eating Disorders Association
March 22, 2019 - Pumping up red blood cell production
March 22, 2019 - Excessive phosphate fertilizer may hurt plants by altering microbial composition in soil
March 22, 2019 - Medical marijuana laws could be improving older Americans’ health, study suggests
March 22, 2019 - Study indicates the benefits of stopping aspirin in heart attack patients
March 22, 2019 - Deep brain stimulation offers significant relief for patients with treatment-resistant depression
March 22, 2019 - Mental health problems in young adults on the rise
March 22, 2019 - Innovative membrane offers a viable solution for periodontitis
March 22, 2019 - The FDA Grants Rare Pediatric Disease Designation to Odiparcil for the Treatment of MPS VI
March 22, 2019 - insulin therapy: MedlinePlus Medical Encyclopedia
March 22, 2019 - Guidelines on the use of genetic testing in psychiatry
March 22, 2019 - Aspiring Doctors Seek Advanced Training In Addiction Medicine
March 22, 2019 - A change in focus could enable the development of new treatments for Alzheimer’s disease
March 22, 2019 - A new way to visualize the immune cell “landscape” of bowel cancer tumors
March 22, 2019 - Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia
March 22, 2019 - Ludwig scientists to share advances in cancer research at AACR Annual Meeting 2019
March 22, 2019 - Less invasive valve replacement can be safe and effective alternative for healthier patients
March 22, 2019 - Aphasia research reveals new, complex interactions between thought and language
March 22, 2019 - Artificial neural networks can predict how different areas in the brain respond to words
March 22, 2019 - Age-related changes to gut microbiome have adverse impact on vascular health, study shows
March 22, 2019 - Study provides new insight into blood cell and immune cell production
March 22, 2019 - Isolated seniors chat online to prevent cognitive decline
Measles can be deadly for people with weakened immune systems

Measles can be deadly for people with weakened immune systems

image_pdfDownload PDFimage_print

Last year, a 26-year-old man receiving treatment for leukemia went to a Swiss hospital’s emergency room with a fever, a sore throat, and a cough, and was admitted. His condition worsened, and 17 days later, he died from severe complications of measles. The man’s weakened immune system was unable to fight off the disease, even though he was vaccinated against measles as a child.

A new report in Open Forum Infectious Diseases describes the man’s case, highlighting the importance of maintaining high vaccination coverage in the community to help protect people with compromised immune systems from measles and other vaccine-preventable infections. “Measles is not harmless, it’s a serious disease,” said the report’s lead author, Philipp Jent, MD, of Bern University Hospital and the University of Bern in Switzerland. “There is a responsibility to vaccinate yourself to protect others, not only to protect yourself.”

Following the patient’s admission in February of 2017, he developed additional symptoms over the next several days, including a progressive rash, mouth sores, and conjunctivitis, that suggested measles, although he had been fully vaccinated against the disease with the recommended two doses of the measles, mumps, and rubella (MMR) vaccine in the 1990s. A throat swab test confirmed the measles infection. Treatment with ribavirin (an antiviral drug), immunoglobulins (a type of antibody), and vitamin A did not improve his condition. He subsequently developed severe pneumonia and died.

The case illustrates how serious measles can be, particularly for people with compromised immune systems due to cancer treatment or other causes. It also underscores the importance of herd immunity in protecting these vulnerable individuals, the report’s authors noted. When vaccination rates in a community are high enough, vaccine-preventable diseases like measles are less likely to spread, which helps protect those who cannot be vaccinated (such as newborns not old enough to be immunized) or, like the patient in this case, for whom vaccines are not as effective.

When the proportion of people in a community who are vaccinated drops below this threshold, however, as it has for measles immunizations in several European countries, outbreaks are more likely. More than 41,000 children and adults in Europe were infected with measles during the first half of 2018, according to the World Health Organization, exceeding the annual total of European cases reported in any previous year this decade. In the U.S., there had been 142 confirmed cases of measles in 2018 as of early October, according to the U.S. Centers for Disease Control and Prevention (CDC). Data released by CDC in October also showed a gradual but concerning climb in the numbers of U.S. children who reach their second birthday without having received any recommended vaccines.

“Ongoing efforts to raise confidence in vaccines and increase population immunity should be intensified,” the authors wrote in the case report’s conclusion. Physicians caring for people with compromised immune systems, the authors noted, should also ensure that those in close contact with these patients, such as family members and friends, are fully vaccinated.

Fast Facts

  • People with weakened immune systems are at risk for contracting vaccine-preventable diseases, such as measles, even if they have been vaccinated.
  • In this case, a 26-year-old Swiss man undergoing treatment for leukemia contracted measles and died from severe complications of the infection, despite being fully vaccinated against measles as a child.
  • Maintaining high enough levels of vaccination coverage in the broader community, also known as herd immunity, can limit the spread of measles and other diseases and help protect those who are especially vulnerable.

Source:

http://www.idsociety.org/

Tagged with:

About author

Related Articles