Breaking News
November 17, 2018 - People with rare cancers can benefit from genomic profiling, shows research
November 17, 2018 - NIH awards over $1.8 million to husband-and-wife doctors to test new breast cancer approach
November 17, 2018 - Four-in-one antibody used to fight flu shows promise in mice
November 17, 2018 - New approach allows pathogens to be starved by blocking important enzymes
November 17, 2018 - Higher body mass index could cause depression even without health problems
November 17, 2018 - Protein which plays role in sensing cell damage serves as new target to treat pulmonary hypertension
November 17, 2018 - FDA Approves Adcetris (brentuximab vedotin) in Combination with Chemotherapy for Adults with Previously Untreated Systemic Anaplastic Large Cell Lymphoma or Other CD30-Expressing Peripheral T-Cell Lymphomas
November 17, 2018 - ID specialist input improves outcomes for outpatient parenteral antimicrobial therapy
November 17, 2018 - UT Southwestern scientists selected to receive 2019 Edith and Peter O’Donnell Awards
November 17, 2018 - New clinical algorithm to help individuals manage type 2 diabetes when fasting during Ramadan
November 17, 2018 - Researchers identify LZTR1 as evolutionarily conserved component of RAS pathway
November 17, 2018 - Heart Disease Leading Cause of Death in Low-Income Counties
November 17, 2018 - Estrogen Levels Test: MedlinePlus Lab Test Information
November 17, 2018 - Research reveals link between immunity, diabetes
November 17, 2018 - Research shows how to achieve improved smoking cessation outcomes within California’s Medicaid population
November 17, 2018 - New study finds less understanding and implementation of patient engagement
November 17, 2018 - New shoe insole technology could help diabetic ulcers heal better while walking
November 17, 2018 - New method to extend cell division and immortalization of avian-derived cells
November 17, 2018 - Australian Academy of Science urges parents to vaccinate children against meningococcal disease
November 17, 2018 - Hot water treatment may help improve inflammation and metabolism in sedentary people
November 17, 2018 - Researchers produce 3D chemical maps of small biological samples
November 17, 2018 - Must Blood Pressure Rise Wth Age? Remote Tribes Hold Clues
November 17, 2018 - Noonan Syndrome
November 17, 2018 - Interventions to delay and prevent type 2 diabetes are underused, researchers say
November 17, 2018 - Hackathon prize winner seeks to remotely monitor patient skin conditions
November 17, 2018 - Research team identifies Ashkenazi Jewish founder mutation for Leigh syndrome
November 17, 2018 - Gene editing could be used to halt kidney disease in patients with Joubert syndrome
November 17, 2018 - Study uncovers link between gut disruption and aging
November 17, 2018 - Teens more likely to pick up smoking after exposure from friends and family
November 17, 2018 - Nicoya designate the Institute for Stem Cell Biology and Regenerative Medicine as the OpenSPR Centre of Excellence
November 17, 2018 - new horizon in dental, oral and craniofacial research
November 17, 2018 - How does poor air quality affect your health?
November 17, 2018 - New device can regulate children’s blood glucose more like natural pancreas
November 17, 2018 - Game-Changers in Western Blotting and Protein Analysis
November 17, 2018 - FDA announces new actions to limit sale of e-cigarettes to youth
November 17, 2018 - Warmer winter temperatures related to higher crime rates
November 17, 2018 - MCO places increasing emphasis on helping people find and access healthy food
November 17, 2018 - Group of students aim to improve malaria diagnosis using old smartphones
November 17, 2018 - Transplantation of feces may protect preterm children from deadly bowel disease
November 17, 2018 - Researchers explore whether low-gluten diets can be recommended for people without allergies
November 17, 2018 - New and better marker for assessing patients after cardiac arrest
November 17, 2018 - For 7-year-old with failing bone marrow, a life-saving transplant | News Center
November 17, 2018 - New first-line treatment for peripheral T-cell lymphoma approved by FDA
November 17, 2018 - Artificial intelligence could be valuable tool to help young victims disclose traumatic testimony
November 17, 2018 - Breakthrough in the treatment of Restless Legs Syndrome
November 16, 2018 - FDA Approves Keytruda (pembrolizumab) for the Treatment of Patients with Hepatocellular Carcinoma (HCC) Who Have Been Previously Treated with Sorafenib
November 16, 2018 - Eagle Books | Native Diabetes Wellness Program
November 16, 2018 - Patients with common heart failure more likely to have lethal heart rhythms
November 16, 2018 - How AI could help veterinarians code their notes | News Center
November 16, 2018 - Bias-based bullying does more harm to students than generalized bullying
November 16, 2018 - Researchers find first direct evidence that cerebellum plays role in cognitive functions
November 16, 2018 - Non-coding genetic variant plays key role in endothelial function and disease incidence
November 16, 2018 - EMA recommends first all-oral treatment to tackle deadly sleeping sickness
November 16, 2018 - Drug used to treat dizziness may slow down growth of triple-negative breast cancer
November 16, 2018 - AHA: Icosapent Ethyl Cuts CV Risk From Elevated Triglycerides
November 16, 2018 - ‘Orphan’ RNAs make cancer deadlier, but potentially easier to diagnose
November 16, 2018 - Air Cube touches down at hospital | News Center
November 16, 2018 - CRISPR-based tool shown to enhance cell-based immunotherapy
November 16, 2018 - Mechanisms that govern HIV latency differ in the gut and blood, finds study
November 16, 2018 - Researchers unravel mystery of NPM1 protein in acute myeloid leukemia
November 16, 2018 - High school students less likely to select milk, fruit for lunch when fruit juice is available
November 16, 2018 - Football coaches with great emotional competence are more successful
November 16, 2018 - Researchers awarded $10 million grant to address root causes of asthma in Puerto Rico
November 16, 2018 - Personalized scheduling of radiotherapy using genetic data could reduce side effects
November 16, 2018 - American Cancer Society study links social isolation to higher mortality risk
November 16, 2018 - Health Tip: Manage Morning Sickness
November 16, 2018 - Long term exposure to road traffic noise linked with greater obesity risk
November 16, 2018 - Infant gut microbes altered by mother’s obesity may increase risk for future disease
November 16, 2018 - Immunotherapy combination and chemotherapy show encouraging results in Phase II acute myeloid leukemia study
November 16, 2018 - ACC Latin America Conference brings experts to discuss latest cardiovascular science
November 16, 2018 - Pooled analysis of Intersect ENT’s steroid releasing implants in patients after frontal sinus surgery to be published
November 16, 2018 - Expectations about pain intensity can become self-fulfilling prophecies
November 16, 2018 - NIH awards $3.4 million to UC researchers to study gastrointestinal lymphatic system
November 16, 2018 - Highlighting Advances in Bioengineering and Analytical Technologies with eBooks
November 16, 2018 - Scientist Dr David Taylor of MR Solutions is a finalist in the BMW i UK Tech Founder Awards
November 16, 2018 - Earlier treatment could help reverse autistic-like behavior in tuberous sclerosis
November 16, 2018 - Sucking your baby’s pacifier could improve their health
November 16, 2018 - Vegetables and salad may include bacteria that are resistant to antibiotics
November 16, 2018 - Autism linked to prolonged connection between brain regions
November 16, 2018 - Endocrine Society chooses four Diabetes Caucus leaders as winners of Diabetes Champion Award
First shared Swiss platform to promote regenerative medicine launched in Bern

First shared Swiss platform to promote regenerative medicine launched in Bern

image_pdfDownload PDFimage_print

Regenerative Medicine is one of the fastest growing sectors in biomedical research – replacing diseased cells, tissues or organs. A national, public-private platform has now been launched in Bern under the name “Translational and Clinical Bio-Manufacturing (TCBM)”. Its goal is to share expertise in the translation of research results into clinical application to promote Regenerative Medicine as well as new cell therapy approaches in Switzerland.

As a Swiss network, the TCBM Platform supports the rapid transfer of research results into clinical applications (translation). Researchers and clinicians from the seven main Swiss universities and university hospitals are working together with industrial partners to promote translation of cellular and cell-related products. Joint workshops and exchange of know-how and ressources will simplify and speed up production processes. Last but not least, training courses will support the eduction of junior researchers.

Further expansion of the Bern as a medical center

For Christian Leumann, Rector of the University of Bern, the TCBM Platform reflects the University of Bern’s long tradition in medicine and health. “This made us an important location for teaching and research in the area of advanced medicine”, Leumann says. “One of our aims is to fill the gap between fundamental research and clinical application. The TCBM Platform is helping us make this happen”.

Prof. Eliane J. Mueller, Head of Molecular Dermatology and Stem Cell Research at the University of Bern and at Bern University Hospital, and Dr. Steffen M. Zeisberger, Director of Quality Assurance and Cell and Tissue Biobanking at Wyss Zurich, are co-leaders of the platform. “This first shared Swiss platform for translational and medical production of biological components is an important step towards future-oriented research for regenerative therapies”, Uwe E. Jocham, President of the Board of Directors of Insel Gruppe AG, says. “The fact that we, as the Bern site of research, are playing a key role with the co-management fills us with pride. Because, with the Bern University Hospital, we want to be at the forefront of stem cell research and translation.”

Exploiting synergies

The national TCBM Platform promotes synergies in translational and clinical production of biological components on three levels: Firstly, research groups using and operating clean rooms cooperate closely in the bio-manufacturing process. Secondly, they share their expertise in good manufacturing practice, and cooperatly negociate with Swiss regulatory authorities. Thirdly, the platform promotes collaborations of research groups with the private sector or industry to facilitate joint applications at Innosuisse, the Swiss agency for innovation promotion, or the Swiss National Science Foundation (SNSF).

Increasing visibility for industry and Innosuisse

The TCBM Platform is affiliated with the national organisation “biotechnet Switzerland”, which in turn is part of the National Thematic Network (NTN) “Swiss Biotech”. NTN represents the interests of the Swiss Biotechnological industry, while biotechnet Switzerland supports biotechnological research groups in academia and conveys their expertise to industrial partners. Through affiliation with biotechnet Switzerland, the TCBM Platform becomes visible for industry and Innosuisse. The TCBM Platform is financed, among others, by membership fees of public and private partners. Its administration is supported by the University of Bern’s Faculty of Medicine. “We value this initiative across Switzerland, which seamlessly incorporates into the translational efforts of the University of Bern. We are therefore committed to ensuring its success”, Hans-Uwe Simon, Dean of the Faculty of Medicine, reiterates.

National and international vision

After the successful launch of the TCBM Platform, new members will now be recruited from the public and private sector and the Advisory Board constituted by personalities from science, industry and regulatory authorities. In cooperation with sitem-insel AG, the Swiss Institute for Translational and Entrepreneurial Medicine, and the emerging Center for Precision Medicine, first workshops and joint activities in the area of cellular therapies are planned for 2019. Mark Rubin, Director of the Department for BioMedical Research (DBMR) at the University of Bern, is looking forward to the cooperation: “The TCBM Platform will significantly enhance the development of our Center for Precision Medicine in Bern. Observations made from patients can be translated to model systems for study and the development of new therapies. I am most excited to welcome the TCBM.”

One of the visions of the TCBM Platform is to start its own National Thematic Network (NTN) in Regenerative Medicine and Cell Therapy with partners of biotechnet Switzerland. Furthermore, the group envisages to apply for a NCCR (National Centres of Competence in Research) at the SNSF, and extend its activities to the EU and other international partners.

Prof. Eliane J. Mueller, Co-Leader of the TCBM Platform: “During the launch ceremony of sitem-insel AG in Bern, Federal Councillor Schneider-Ammann praised Bern for switching from user to provider in the area of translational medicine in Switzerland. I think the industry should take heed of this upward trend.”

Source:

http://www.unibe.ch/news/media_news/media_relations_e/media_releases/2018/medienmitteilungen_2018/switzerland_wide_platform_for_cell_therapy_launched_in_bern/index_eng.html

Tagged with:

About author

Related Articles