Breaking News
December 13, 2018 - NIH offers support for HIV care and prevention research in the southern United States
December 12, 2018 - Activating brain region could revive the urge to socialize among opioid addicts
December 12, 2018 - Relationship impairment appears to interfere with seeking mental health treatment in men
December 12, 2018 - Sleep, Don’t Cram, Before Finals for Better Grades
December 12, 2018 - Effective treatments for urticarial vasculitis
December 12, 2018 - Gun violence is a public health issue: One physician’s story
December 12, 2018 - The Science of Healthy Aging
December 12, 2018 - Yes to yoghurt and cheese: New improved Mediterranean diet
December 12, 2018 - Researchers uncover a number of previously unknown insecticide resistance mechanisms
December 12, 2018 - Regulating the immune system’s ‘regulator’
December 12, 2018 - In breaking bad news, the comfort of silence
December 12, 2018 - Study finds upward link between alcohol consumption and physical activity in college students
December 12, 2018 - FDA issues warning letter to Zhejiang Huahai Pharmaceutical involved in valsartan recall
December 12, 2018 - Presence of antiphospholipid antibodies tied to first-time MI
December 12, 2018 - New study could help inform research on preventing falls
December 12, 2018 - Women and men with heart attack symptoms receive different care from EMS
December 12, 2018 - Disrupted biological clock can contribute to onset of diseases, USC study shows
December 12, 2018 - New publications generate controversy over the value of reducing salt consumption in populations
December 12, 2018 - New data from TAILORx trial confirms lack of chemo benefit regardless of race or ethnicity
December 12, 2018 - Specific class of biomarkers can accurately indicate the severity of cancer
December 12, 2018 - Meds Taken Do Not Vary With ADL Impairment in Heart Failure
December 12, 2018 - Long-term study shows that HIV-2 is deadlier than previously thought
December 12, 2018 - People living near oil and gas wells show early signs of cardiovascular disease
December 12, 2018 - IONTAS founder and pioneer in phage display technology attends Nobel Prize Award Ceremony
December 12, 2018 - People who eat red meat have high levels of chemical associated with heart disease, study finds
December 12, 2018 - New method uses water molecules to unlock neurons’ secrets
December 12, 2018 - Genetics study offers hope for new acne treatment
December 12, 2018 - New computer model predicts prostate cancer progression
December 12, 2018 - Nobel Laureates lecture about immune checkpoint therapy for cancer treatment
December 12, 2018 - More Illnesses From Tainted Romaine Lettuce Reported
December 12, 2018 - Aspirin could reduce HIV infections in women
December 12, 2018 - The EORTC Brain Tumor Group and Protagen AG collaborate to study immuno-competence of long-term glioblastoma survivors
December 12, 2018 - Insights into magnetotactic bacteria could guide development of biological nanorobots
December 12, 2018 - Sacrificial immune cells alert body to infection
December 12, 2018 - Low-salt diet may be more beneficial for females than males
December 12, 2018 - Major soil organic matter compound battles chronic wasting disease
December 12, 2018 - Findings may open up new ways to treat dwarfism and other ER-stress-related conditions
December 12, 2018 - New computational model provides clearer picture of shape-changing cells’ structure and mechanics
December 12, 2018 - 10 Facts on Patient Safety
December 12, 2018 - Poorest dying nearly 10 years younger than the rich in ‘deeply worrying’ trend for UK
December 12, 2018 - Innovative care model for children with ASD reduces use of behavioral drugs in ED
December 12, 2018 - Spending time in and around Hong Kong’s waters linked to better health and wellbeing
December 12, 2018 - Simple measures to prevent weight gain over Christmas
December 12, 2018 - Research advances offer hope for patient-tailored AML treatment
December 12, 2018 - Researchers discover a ‘blind spot’ in atomic force microscopy
December 12, 2018 - Sprayable gel could help prevent recurrences of cancer after surgery
December 12, 2018 - SLU researchers explore how fetal exposure to inflammation can alter immunity in newborns
December 12, 2018 - How do patients want to discuss symptoms with clinicians?
December 12, 2018 - Zinc chelation may be able to deliver drug to insulin-producing cells
December 12, 2018 - Brigham researchers develop automated, low-cost tool to predict a woman’s ovulation
December 12, 2018 - Some people with Type 2 diabetes may be testing their blood sugar more often than needed
December 12, 2018 - Slow-growing type of glioma may be vulnerable to immunotherapy, suggests study
December 12, 2018 - Study provides new information regarding microRNA function in cellular homeostasis of zebrafish
December 12, 2018 - Study provides new understanding of mysterious ‘hereditary swelling’
December 12, 2018 - Researchers shed new light on how to combat Shiga and ricin toxins
December 12, 2018 - Pregnant Women Commonly Refuse Vaccines
December 12, 2018 - Drug treatment could offer new hope for some patients with brain bleeding
December 12, 2018 - Health care financial burden of animal-related injuries is growing, study says
December 12, 2018 - Macrophage cells could help repair the heart following a heart attack, study finds
December 12, 2018 - Researchers develop new system for efficiently producing human norovirus
December 12, 2018 - New artificial intelligence-based system to differentiate between different types of cancer cells
December 11, 2018 - Brazilian professors propose guidelines for therapeutic use of melatonin
December 11, 2018 - Healthy Lifestyle Lowers Odds of Breast Cancer’s Return
December 11, 2018 - New research identifies two genes linked to serious congenital heart condition
December 11, 2018 - NIH Director talks science, STEM careers with preteens
December 11, 2018 - Disabling a Cellular Antivirus System Could Improve Gene Therapy
December 11, 2018 - New tool swiftly provides accurate measure of patients’ cognitive difficulties
December 11, 2018 - NICE releases new guidelines for diagnosis and management of COPD
December 11, 2018 - Without Obamacare penalty, think it’ll be nice to drop your plan? Better think twice
December 11, 2018 - Researchers capture high-resolution X-ray and NMR image of key immune regulator
December 11, 2018 - Natural flavonoid is effective at treating leishmanisis infections, study shows
December 11, 2018 - Avoidant grievers unconsciously monitor and block mind-wandering contents, study shows
December 11, 2018 - Study identifies how hantaviruses infect lung cells
December 11, 2018 - Improving PTSD care through genetics
December 11, 2018 - Dermatology providers show interest in recommending cannabinoids to patients
December 11, 2018 - Researchers to study effects of electroconvulsive therapy on Alzheimer’s patients with aggression
December 11, 2018 - Four dried fruits have lower glycemic index than starchy foods, study finds
December 11, 2018 - Optimization of drug dose sizes can reduce pharmaceutical wastage
December 11, 2018 - Ultrarestrictive opioid prescribing strategy linked with reduction in number of pills dispensed
December 11, 2018 - PET scans to optimize tuberculosis meningitis treatments and personalize care, study finds
Bacteria in babies’ noses could offer clues to recovery from first cough or cold

Bacteria in babies’ noses could offer clues to recovery from first cough or cold

image_pdfDownload PDFimage_print

New research on the types of bacteria living in babies’ noses could offer clues as to why some recover quickly from their first cough or cold, while others suffer for longer.

The study, published in ERJ Open Research, suggests that babies who have a wide variety of different bacteria living in their noses tend to recover more quickly from their first respiratory virus, compared to those who have less variety and more bacteria from either the Moraxellaceae or Streptococcaceae family.

The researchers say their findings do not offer an immediate solution to help babies recover more quickly from coughs and colds. However, the results could help scientists understand the importance of the bacteria living in the respiratory tract, and how they influence infections and longer term conditions such as asthma.

Dr Roland P Neumann from University Children’s Hospital of Basel, University of Basel, Switzerland, was one of the researchers. He explained: “It’s well known that different types of bacteria live in our gut. The respiratory tract is also home to a wide variety of bacteria and we are beginning to understand that the types and numbers of these bacteria, what we refer to as the microbiota, can influence our respiratory health.

“We know that babies often suffer with coughs, runny noses, sore throats and ear infections, and in some babies the symptoms seem to drag on for weeks. These are usually caused by a virus such as the common cold, but we wanted to investigate whether the microbiota of the nose might also have a role in how long symptoms last. This is important not only in terms of babies feeling unwell but also because respiratory infections in the early years are linked to the development of asthma in later life.”

The research was part of a larger study that is following a group of babies from birth to investigate the complex interactions of genetic and environmental factors and their influence on lung health.

Parents taking part in this part of the study were asked to contact the researchers as soon as their babies developed symptoms of their first respiratory infection. This included more than two consecutive days when their babies were coughing, had a runny nose, signs of an ear infection or sore throat.

Researchers took swabs from the noses of babies at that point and then took swabs again three weeks later. They analysed the swabs by testing for the presence of respiratory viruses, such as the common cold, and for the types of numbers of different bacteria.

Working with sets of swabs from 183 babies, researchers were able to group the babies according to the makeup of their nasal microbiota.

On average, the babies’ symptoms lasted around two weeks. Babies who were free of symptoms by the time the three-week swab was taken were more likely to have a wider mixture of bacteria in their noses and a microbiota that was not dominated by bacteria from the Moraxellaceae or Streptococcaceae family.

Among babies whose symptoms lasted three weeks or longer, researchers found less variety in the types of bacteria living in the babies’ noses and the microbiota were more likely to be dominated by bacteria from the Moraxellaceae or Streptococcaceae family. These families include specific types that are known to be linked with respiratory disease.

They found no clear link between the type of respiratory virus and the persistence of symptoms.

Researchers took account of other factors that are known to have an impact on respiratory health, including the babies age, the season of the year, whether they had siblings or attended nursery, and whether they were exposed to cigarette smoke.

They say this study cannot explain why the link exists, but a possible explanation is that certain types of bacteria may be more likely to result in inflammation and a worsening in symptoms. Or, it could be that a more diverse set of bacteria offers some protective effect.

Professor Urs Frey, Chair of Paediatrics at the University Children’s Hospital of Basel, University of Basel, Switzerland, was also a researcher on the study. He said: “This study helps us to understand how bacteria that naturally live in the upper airways are important for respiratory health.

“We know that antibiotics and environmental factors, such as season and childcare, can alter the numbers and types of bacteria in babies’ noses. We do not yet know what combination of bacteria would be ‘ideal’ and this would need to be known before we understand how we might manipulate it.”

Professor Tobias Welte, from Hannover University, Germany, is President of the European Respiratory Society and was not involved in the study. He said: “There is an association between respiratory symptoms in babies in the first year of life and the development of asthma by school-age. We do not yet fully understand this link but the bacteria living in the upper airways could play a role. We need to do more research to understand the relationship between these bacteria, respiratory infections and long-term lung health.”

Source:

http://www.europeanlung.org/en/

Tagged with:

About author

Related Articles