Virginia Tech Carilion Research Institute scientists have shown that mutations in specific genes that destroy motor neurons and thereby cause the devastating effects of amyotrophic lateral sclerosis– also known as ALS or Lou Gehrig’s disease — also attack sensory neurons. The discovery in today’s (Thursday, Nov. 8) Scientific Reports indicates that studying sensory neurons could […]Continue Reading ...
3D reconstruction of electron microscopy images showing a perinodal astrocyte (blue), node of Ranvier (gray), compact myelin (purple), and layers of myelin detaching from the axon (tan). Credit: Fields Laboratory, NICHD/NIH The transmission speed of neurons fluctuates in the brain to achieve an optimal flow of information required for day-to-day activities, according to a National […]Continue Reading ...
Houston Methodist researchers have discovered a repair defect in nerve cells that send messages to the brain, opening the door to a possible therapy for preventing or slowing down ALS. Also known as Lou Gehrig’s disease, ALS is a terminal illness marked by rapidly progressive muscle weakness that ultimately affects a person’s ability to swallow […]Continue Reading ...
Oct 19 2018 Human neurons are much larger than those of model organisms mice and rats, so it’s been unclear whether it’s size that makes a difference in our brain’s computational power. Now, in a study appearing October 18 in the journal Cell, researchers show that unlike those of other animals, human neurons employ highly […]Continue Reading ...
UT Southwestern researchers attempting to transform supporting brain cells into neurons instead reprogrammed mature inhibitory neurons into a different type of neuron that creates the neurotransmitter lost in Parkinson’s disease. The study, published today in Stem Cell Reports, reveals the possibility of changing mature neurons from one kind to another without relying on stem cells, […]Continue Reading ...
It’s about the size of a dinner table; yet, one day may influence conversations held around the kitchen table. This is what excites researchers at the University of Texas at San Antonio as they anticipate the arrival of a state-of-the-art microscope. This device, known to a very select few, as a two-photon holographic microscope, will […]Continue Reading ...
Brown University researchers have uncovered new clues about the progression of Amyotrophic Lateral Sclerosis (ALS), a surprisingly common disease that causes the death of motor neurons that control voluntary muscles such as those involved in walking, talking, chewing or breathing. A team led by Anne Hart, a professor of neuroscience at Brown, discovered that two […]Continue Reading ...
Parkinson’s disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness. Identifying the genes that underlie the loss of these neurons is important to understanding how the disease functions, according to Patrick Cunningham, a […]Continue Reading ...
When you park in the office car park, you usually have no problem finding your car again at the end of the day. The next day, you might park a few spots further away. However, in the evening, you find your car, even though the memories of both days are very similar. You find your […]Continue Reading ...
Single neurons in the brain’s primary visual cortex can reliably detect straight lines, even though the cellular makeup of the neurons is constantly changing, according to a new study by Carnegie Mellon University neuroscientists, led by Associate Professor of Biological Sciences Sandra Kuhlman. The study’s findings, published in Scientific Reports on Oct. 16, lay the […]Continue Reading ...
Illustration depicting transcribed noncoding elements (TNE or enhancer RNAs) in the brain Credit: Clemens Scherzer, Brigham and Women’s Hospital Dopamine neurons are located in the midbrain, but their tendril-like axons can branch far into the higher cortical areas, influencing how we move and how we feel. New genetic evidence has revealed that these specialized cells […]Continue Reading ...
Oct 12 2018 Attempting to make dopamine-producing neurons out of glial cells in mouse brains, a group of researchers instead converted mature inhibitory neurons into dopaminergic cells. Their findings, appearing October 11 in the journal Stem Cell Reports, reveal that–contrary to previous belief–it is possible to reprogram one mature neuron type into another without first […]Continue Reading ...
The National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health has awarded Andrea Bertke, an assistant professor of infectious diseases in the Department of Population Health Sciences in the Virginia-Maryland College of Veterinary Medicine at Virginia Tech, $1.7 million to study the neuron-specific regulation of herpes simplex viruses 1 and […]Continue Reading ...
Researchers at VIB and KU Leuven have uncovered a new molecular interaction that governs the formation of specific functional connections between two types of neurons. It gives an important clue as to how unique interactions give shape to precisely organized neuronal networks in the brain. Pyramidal neurons are named after their cell body, which is […]Continue Reading ...
Research published today in the journal Cell suggests that viruses known to target the central nervous system may also affect neurons of the digestive tract, causing intestinal blockages and abdominal pain. Image Credit: Rost9 / Shutterstock Abdominal pain is one of the most common ailments for which patients seek relief and is notoriously difficult to […]Continue Reading ...
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