Mar 12 2019 Individual neurons in the monkey amygdala that respond to touch also respond to imagery and sounds, according to new research published in JNeurosci. These cells may provide the building blocks needed to process multisensory social and emotional information. Previous studies of the amygdala have identified populations of neurons responsive to different types […]Continue Reading ...
It’s easy to miss something you’re not looking for. In a famous example, people were asked to closely observe two groups of people–one group clad in black, the other in white–pass a ball among themselves. Viewers were asked to count the number of times the ball passed from black to white. Remarkably, most observers did […]Continue Reading ...
Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats–with the flip of a switch. The researchers were able to use lasers to temporarily inactivate a specific neuronal population, reversing alcohol-seeking behavior and even reducing the physical symptoms of withdrawal. “This discovery is exciting–it means we have another […]Continue Reading ...
Loss of dopaminergic neurons is a hallmark of Parkinson’s disease pathology. When dopaminergic neurons are stressed, they send out a call for help to nearby glial cells that are tasked with providing neuronal support, protection and nourishment. Under particular molecular conditions, those calls for help can over-activate the glial cells, resulting in a cascade of […]Continue Reading ...
Neurons in the rat nucleus accumbens — a key brain reward structure — were targeted for CRISPR-based gene activation. Fluorescent reporter molecules mark the protein product of a gene targeted for activation (green), neurons expressing a CRISPR guide RNA (red), and DNA (blue). Credit: Katherine Savell and Nancy Carullo, UAB A powerful new tool is […]Continue Reading ...
The tool, called CaImAn, replaces the process of manually tracking the location and activity of neurons Tracking the firings of individual neurons is like trying to discern who is saying what in a football stadium full of screaming fans. Until recently, neuroscientists have had to tediously track each neuron by hand. “People spent more time […]Continue Reading ...
Brain cells recorded as among the least electrically active during a specific task may be the most important to doing it right. Results of new experiments in rodents, led by neuroscientists at NYU School of Medicine, challenge the assumption in brain research that the most active brain cells, or neurons, involved in any complex activity […]Continue Reading ...
Directly activating a gene important to exciting our excitatory neurons and associated with major depression may help turn around classic symptoms like social isolation and loss of interest, at least for males, scientists report. They looked in the prefrontal cortex, a brain area involved in complex behaviors like planning, personality and social behavior and known […]Continue Reading ...
Researchers at the Scripps Research Institute have made an important discovery that may help to explain the neural mechanism that drives alcohol consumption in cases of addiction. Shutterstock | bluedog studio In a rat model of alcohol-dependency, the team found they could reverse the urge to drink by inactivating a specific subset of nerve cells […]Continue Reading ...
It’s been estimated that the human brain contains roughly 100 billion neurons, together completing countless tasks through countless connections. So how do we make sense of the roles each of these neurons play? As part of the United States BRAIN Initiative, scientists from Cold Spring Harbor Laboratory (CSHL) have outlined a way to classify neurons […]Continue Reading ...
Researchers discover how brain cells in the microscopic worm, C. elegans send electrical signals It’s the small pieces that make the big picture, and in this case, the pieces can’t be seen by the naked eye. New research at the Okinawa Institute of Science and Technology Graduate University (OIST) used microscopy techniques to piece together […]Continue Reading ...
Neuroscientists will no longer have to track neural activity by hand thanks to invaluable open-source software CaImAn, which automates the process with near-human accuracy. This is an image of neurons (white) taken using calcium imaging techniques. An innovative software dubbed CaImAn can automatically differentiate between individual neurons (yellow outlines) with nearly the same accuracy as […]Continue Reading ...
Scientists of the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Goettingen (UMG) have been able to alleviate motor disorders in mice that resemble those seen in Parkinson’s patients. The rodents were treated with a substance that affects the neurons and immune cells of the brain. If this novel approach proves to […]Continue Reading ...
The UCLA scientists observed consistent bursts of electrical activity in the developing brain of fruit flies. T4 and T5 indicate individual neurons firing. Credit: Akin Lab/UCLA Health Neurons somehow know which of their neighbors to connect with and which to avoid in the crowded environment of the central nervous system. But how? Using fruit flies, […]Continue Reading ...
Feb 15 2019 Genetic variation in individual neurons may have big effect as we age Scientists at the University of Virginia School of Medicine have identified a potential explanation for the mysterious death of specific brain cells seen in Alzheimer’s, Parkinson’s and other neurodegenerative diseases. Genetic variations inside individual neurons may explain the mysterious cell […]Continue Reading ...
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